ProSci

NR1D2 Antibody

Product Code:
 
PSI-58-042
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
1 / 2
Western blot analysis in Hela cell line lysates (35ug/lane).
2 / 2
NR1D2 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
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Western blot analysis in Hela cell line lysates (35ug/lane).
NR1D2 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

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PSI-58-042-400ul400ul£626.00
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Further Information

Additional Names:
Nuclear receptor subfamily 1 group D member 2, Orphan nuclear hormone receptor BD73, Rev-erb alpha-related receptor, RVR, Rev-erb-beta, V-erbA-related protein 1-related, EAR-1R, NR1D2
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
This gene encodes a member of the nuclear hormone receptor family, specifically the NR1 subfamily of receptors. The encoded protein functions as a transcriptional repressor and may play a role in circadian rhythms and carbohydrate and lipid metabolism. Alternatively spliced transcript variants have been described.
Background References:
  • Campos-de-Sousa, S., et al. J. Biol. Rhythms 25(2):132-137(2010)
  • Burris, T.P. Mol. Endocrinol. 22(7):1509-1520(2008)
  • Liu, A.C., et al. PLoS Genet.(2), E1000023 (2008) :
  • Wang, J., et al. Biochim. Biophys. Acta 1783(2):224-236(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This NR1D2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 266-294 amino acids from the Central region of human NR1D2.
NCBI Gene ID #:
9975
NCBI Official Name:
Nuclear receptor subfamily 1 group D member 2
NCBI Official Symbol:
NR1D2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
65 kDa
Protein Accession #:
Q14995
Protein GI Number:
215274122
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q14995
User NOte:
Optimal dilutions for each application to be determined by the researcher.