Further Information
Probable ATP-dependent RNA helicase DDX11, CHL1-related protein 1, hCHLR1, DEAD/H box protein 11, Keratinocyte growth factor-regulated gene 2 protein, KRG-2, DDX11, CHL1, CHLR1, KRG2
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
DEAD box proteins, characterized by the conserved motif
Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are
implicated in a number of cellular processes involving alteration
of RNA secondary structure such as translation initiation, nuclear
and mitochondrial splicing, and ribosome and spliceosome assembly.
Based on their distribution patterns, some members of this family
are believed to be involved in embryogenesis, spermatogenesis, and
cellular growth and division. DDX11 encodes a DEAD box protein,
which is an enzyme that possesses both ATPase and DNA helicase
activities. DDX11 is a homolog of the yeast CHL1 gene, and may
function to maintain chromosome transmission fidelity and genome
stability.
- Leman, A.R., et al. J. Cell. Sci. 123 (PT 5), 660-670 (2010) :
- Farina, A., et al. J. Biol. Chem. 283(30):20925-20936(2008)
- Parish, J.L., et al. Mol. Cell 24(6):867-876(2006)
- Parish, J.L., et al. J. Cell. Sci. 119 (PT 23), 4857-4865 (2006) :
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
This DDX11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 656-683 amino acids from the Central region of human DDX11.
1663
Probable ATP-dependent RNA helicase DDX11
DDX11
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
108 kDa
Q96FC9
74731686
This antibody is purified through a protein A column, followed by peptide affinity purification.
Cell Cycle
Q96FC9
Optimal dilutions for each application to be determined by the researcher.
