Further Information
Probable ATP-dependent RNA helicase DDX4, DEAD box protein 4, Vasa homolog, DDX4, VASA
For WB starting dilution is: 1:1000
DEAD box proteins, characterized by the conserved motif
Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are
implicated in a number of cellular processes involving alteration
of RNA secondary structure such as translation initiation, nuclear
and mitochondrial splicing, and ribosome and spliceosome assembly.
Based on their distribution patterns, some members of this family
are believed to be involved in embryogenesis, spermatogenesis, and
cellular growth and division. This gene encodes a DEAD box protein,
which is a homolog of VASA proteins in Drosophila and several other
species. The gene is specifically expressed in the germ cell
lineage in both sexes and functions in germ cell development.
Multiple transcript variants encoding different isoforms have been
found for this gene.
- Tilgner, K., et al. Stem Cells 28(1):84-92(2010)
- Sugimoto, K., et al. J. Hum. Genet. 54(8):450-456(2009)
- Hashimoto, H., et al. Gynecol. Oncol. 111(2):312-319(2008)
- Albamonte, M.S., et al. Hum. Reprod. 23(8):1895-1901(2008)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Monkey
This DDX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-131 amino acids from the N-terminal region of human DDX4.
54514
Probable ATP-dependent RNA helicase DDX4
DDX4
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
79 kDa
Q9NQI0
20138033
This antibody is purified through a protein A column, followed by peptide affinity purification.
Cell Cycle,Signal Transduction
Q9NQI0
Optimal dilutions for each application to be determined by the researcher.