ProSci

UNC119 Antibody

Product Code:
 
PSI-63-914
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis of UNC119 Antibody in mouse testis tissue lysates (35ug/lane)
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Formalin-fixed and paraffin-embedded human testis tissue reacted with UNC119 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
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Western blot analysis of UNC119 Antibody in mouse testis tissue lysates (35ug/lane)
Formalin-fixed and paraffin-embedded human testis tissue reacted with UNC119 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

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PSI-63-914-400ul400ul£626.00
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Further Information

Additional Names:
Protein unc-119 homolog A, Retinal protein 4, hRG4, UNC119, RG4
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100
Background:
UNC119 is specifically expressed in the photoreceptors in the retina. The encoded product shares strong homology with the C. elegans unc119 protein and it can functionally complement the C. elegans unc119 mutation. It has been localized to the photoreceptor synapses in the outer plexiform layer of the retina, and suggested to play a role in the mechanism of photoreceptor neurotransmitter release through the synaptic vesicle cycle.
Background References:
  • Karim, Z., et al. Cell. Signal. 22(1):128-137(2010)
  • Gorska, M.M., et al. J. Immunol. 183(3):1675-1684(2009)
  • Vepachedu, R., et al. J. Immunol. 179(1):682-690(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Rat
Immunogen:
This UNC119 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-94 amino acids from the Central region of human UNC119.
NCBI Gene ID #:
9094
NCBI Official Name:
Protein unc-119 homolog A
NCBI Official Symbol:
UNC119
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
27 kDa
Protein Accession #:
Q13432
Protein GI Number:
2498854
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Neuroscience
Swissprot #:
Q13432
User NOte:
Optimal dilutions for each application to be determined by the researcher.