ProSci

Mouse Tgfbr1 Antibody

Product Code:
 
PSI-57-980
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in mouse kidney tissue lysates (35ug/lane).
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Western blot analysis in mouse kidney tissue lysates (35ug/lane).

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PSI-57-980-400ul400ul£626.00
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Further Information

Additional Names:
TGF-beta receptor type-1, TGFR-1, ESK2, Transforming growth factor-beta receptor type I, TGF-beta receptor type I, TbetaR-I, Tgfbr1
Application Note:
For WB starting dilution is: 1:1000
Background:
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta.
Background References:
  • Ghoreschi, K., et al. Nature 467(7318):967-971(2010)
  • Kel, J.M., et al. J. Immunol. 185(6):3248-3255(2010)
  • Droguett, R., et al. Exp. Cell Res. 316(15):2487-2503(2010)
  • Moreno, S.G., et al. Dev. Biol. 342(1):74-84(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Human, Pig, Rat
Immunogen:
This Mouse Tgfbr1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 141-169 amino acids from the Central region of mouse Tgfbr1.
NCBI Gene ID #:
21812
NCBI Official Name:
TGF-beta receptor type-1
NCBI Official Symbol:
Tgfbr1
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
56 kDa
Protein Accession #:
Q64729
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
Q64729
User NOte:
Optimal dilutions for each application to be determined by the researcher.