ProSci

SLC25A20 Antibody

Product Code:
 
PSI-60-334
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in mouse cerebellum tissue lysates (35ug/lane).
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Western blot analysis in mouse cerebellum tissue lysates (35ug/lane).

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PSI-60-334-400ul400ul£626.00
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Further Information

Additional Names:
Mitochondrial carnitine/acylcarnitine carrier protein, Carnitine/acylcarnitine translocase, CAC, Solute carrier family 25 member 20, SLC25A20, CAC, CACT
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene product is one of several closely related mitochondrial-membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. This protein mediates the transport of acylcarnitines into mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway. Mutations in this gene are associated with carnitine-acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants.
Background References:
  • Tachibana, K., et al. Biochem. Biophys. Res. Commun. 389(3):501-505(2009)
  • De Lucas, J.R., et al. Mol. Membr. Biol. 25(2):152-163(2008)
  • Pierre, G., et al. J. Inherit. Metab. Dis. 30 (5), 815 (2007) :
  • Peluso, G., et al. J. Cell. Physiol. 203(2):439-446(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SLC25A20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 235-264 amino acids from the C-terminal region of human SLC25A20.
NCBI Gene ID #:
788
NCBI Official Name:
Mitochondrial carnitine/acylcarnitine carrier protein
NCBI Official Symbol:
SLC25A20
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
33 kDa
Protein Accession #:
O43772
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
O43772
User NOte:
Optimal dilutions for each application to be determined by the researcher.