ProSci

PKD2 Antibody

Product Code:
 
PSI-58-019
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in mouse lung tissue lysates (35ug/lane).
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Western blot analysis in mouse lung tissue lysates (35ug/lane).

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PSI-58-019-400ul400ul£626.00
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This product comes from: United States.
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Further Information

Additional Names:
Polycystin-2, Autosomal dominant polycystic kidney disease type II protein, Polycystic kidney disease 2 protein, Polycystwin, R48321, PKD2
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. The encoded protein may function in renal tubular development, morphology, and function, and may modulate intracellular calcium homoeostasis and other signal transduction pathways. This protein interacts with polycystin 1 to produce cation-permeable currents. Mutations in this gene have been associated with autosomal dominant polycystic kidney disease.
Background References:
  • Duning, K., et al. J. Biol. Chem. 285(44):33584-33588(2010)
  • Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
  • Stewart, A.P., et al. Biophys. J. 99(3):790-797(2010)
  • Petri, E.T., et al. Proc. Natl. Acad. Sci. U.S.A. 107(20):9176-9181(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PKD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 874-903 amino acids from the C-terminal region of human PKD2.
NCBI Gene ID #:
5311
NCBI Official Name:
Polycystin-2
NCBI Official Symbol:
PKD2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
110 kDa
Protein Accession #:
Q13563
Protein GI Number:
116242717
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity,Signal Transduction
Swissprot #:
Q13563
User NOte:
Optimal dilutions for each application to be determined by the researcher.