ProSci

NKD1 Antibody

Product Code:
 
PSI-57-158
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in mouse lung,heart,bladder tissue lysates (35ug/lane).
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Western blot analysis in mouse lung,heart,bladder tissue lysates (35ug/lane).

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PSI-57-158-400ul400ul£626.00
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Further Information

Additional Names:
Protein naked cuticle homolog 1, Naked-1, hNkd, hNkd1, NKD1, NKD
Application Note:
For WB starting dilution is: 1:1000
Background:
In the mouse, Nkd is a Dishevelled (see DVL1; MIM 601365)-binding protein that functions as a negative regulator of the Wnt (see WNT1; MIM 164820)-beta-catenin (see MIM 116806)-Tcf (see MIM 602272) signaling pathway.
Background References:
  • Guo, J., et al. PLoS ONE(11), E7982 (2009)Creyghton, M.P., et al. Proc. Natl. Acad. Sci. U.S.A. 103(14):5397-5402(2006) Creyghton, M.P., et al. Genes Dev. 19(3):376-386(2005) Yan, D., et al. Proc. Natl. Acad. Sci. U.S.A. 98(26):14973-14978(2001) Katoh, M. Int. J. Oncol. 19(5):963-969(2001)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This NKD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 83-111 amino acids from the N-terminal region of human NKD1.
NCBI Gene ID #:
85407
NCBI Official Name:
Protein naked cuticle homolog 1
NCBI Official Symbol:
NKD1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
52 kDa
Protein Accession #:
Q969G9
Protein GI Number:
74731040
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q969G9
User NOte:
Optimal dilutions for each application to be determined by the researcher.