ProSci

M-CSF Recombinant Protein

Product Code:
 
PSI-96-923
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
 

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PSI-96-923-0.05mg0.05mg£729.00
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Further Information

Additional Names:
M-CSF,CSF-1,Lanimostim
Application Note:
This recombinant protein can be used for E, WB. For research use only.
Background:
The colony stimulating factor 1 (CSF1), also known as macrophage colony-stimulating factor (M-CSF), is a secreted cytokine which influences hematopoietic stem cells to differentiate into macrophages or other related cell types. Eukaryotic cells also produce M-CSF in order to combat intercellular viral infection. It is one of the three experimentally described colony-stimulating factors. M-CSF binds to the colony stimulating factor 1 receptor. Macrophage colony-stimulating factor has been shown to interact with PIK3R2. M-CSF (or CSF-1) is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells. Locally produced M-CSF in the vessel wall contributes to the development and progression of atherosclerosis.
Background References:
  • Sapi E., 2004, Exp. Biol. Med., 229 : 1-11.
  • Jang Mei-Huei, 2006, The Journal of Immunology, 177 (6): 4055-4063.
  • Cao, Qi, 2014, Kidney International, 85 (4): 794-806.
Biological Activity:
Measured by its binding ability in a functional ELISA. Immobilized Human M-CSF, His Tag at 5 ug/mL (100 uL/well) can bind Human M-CSF R, Fc Tag with a linear range of 0.17-1.52 ng/mL.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
1435
NCBI Official Name:
Colony stimulating factor 1 (macrophage)
NCBI Official Symbol:
M-CSF
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
26 kDa
Protein Accession #:
P09603-1
Purity:
>95% as determined by SDS-PAGE.

Endotoxin level is less than 1.0 EU per ug by the LAL method.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
P09603-1

Documents