ProSci

Glycoprotein / GP (virus) Recombinant Protein

Product Code:
 
PSI-97-054
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Cytomegalovirus (CMV)
Application:
 
Western Blot (WB)
Storage:
 
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
 

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PSI-97-054-0.05mg0.05mg£729.00
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Further Information

Additional Names:
HRSV Glycoprotein G
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Human respiratory syncytial virus (HRSV) is the most common etiological agent of acute lower respiratory tract disease in infants and can cause repeated infections throughout life. Human respiratory syncytial virus A (strain Long) major surface glycoprotein G (RSV-G), a member of the pneumoviruses glycoprotein G family, is also known as attachment glycoprotein G and membrane-bound glycoprotein (mG), which contains a linear heparin binding domain essential for virus attachment to the host. Concretely speaking, RSV-G can attache the virion to the host cell membrane by interacting with heparan sulfate, initiating the infection. Furthermore, RSV-G can also interact with host CX3CR1, the receptor for the CX3C chemokine fractalkine, to modulate the immune response and facilitate infection. Unlike the other paramyxovirus attachment proteins, RSV-G lacks both neuraminidase and hemagglutinating activities.
Background References:
  • Hendricks D.A., et al., 1986, J. Gen. Virol. 68:1705-1714.
  • Bao X., et al., 2008, PLoS Pathog. 4 (5): e1000077.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
144411
NCBI Official Name:
Major surface glycoprotein G
NCBI Official Symbol:
Glycoprotein / GP (virus)
NCBI Organism:
Human respiratory syncytial virus A (strain Long)
Physical State:
Lyophilized
Predicted Molecular Weight:
26.2 kDa
Protein Accession #:
P20895
Purity:
>90% as determined by SDS-PAGE.

Endotoxin level is less than 1.0 EU per ug by the LAL method.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
P20895

Documents