ProSci

LILRB4 Recombinant Protein

Product Code:
 
PSI-96-809
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Cynomolgus Monkey
Application:
 
Western Blot (WB)
Storage:
 
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
 

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PSI-96-809-0.1mg0.1mg£867.00
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Further Information

Additional Names:
LILRB4,ILT3,LIR5,CD85K,HM18
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Leukocyte immunoglobulin-like receptor subfamily B member 4 (LILRB4) is also known as CD85 antigen-like family member K (CD85K), Immunoglobulin-like transcript 3 (ILT-3), Leukocyte immunoglobulin-like receptor 5 (LIR-5), Monocyte inhibitory receptor HM18, which belongs to the leukocyte immunoglobulin-like receptor (LIR) family. LILRB4 / CD85K contains 2 Ig-like C2-type (immunoglobulin-like) domains. CD85K is detected in monocytes, macrophages, dendritic cells, lung, natural killer cells and B-cells. LILRB4 / CD85K is receptor for class I MHC antigens. CD85K recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles, involved in the down-regulation of the immune response and the development of tolerance. LILRB4 interferes with TNFRSF5-signaling and NF-kappa-B up-regulation and inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
Background References:
  • Cella M., et al., 1997, J. Exp. Med. 185:1743-1751.
  • Chang C.C., et al., 2002, Nat. Immunol. 3:237-243.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
107128256
NCBI Official Name:
leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X1
NCBI Official Symbol:
LILRB4
NCBI Organism:
Macaca fascicularis?
Physical State:
Lyophilized
Predicted Molecular Weight:
28.0 kDa
Purity:
>90% as determined by SDS-PAGE.

Endotoxin level is less than 1.0 EU per ug by the LAL method.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
XP_015297198.1

Documents