ProSci

CD155 Recombinant Protein

Product Code:
 
PSI-96-841
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
 

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PSI-96-841-0.1mg0.1mg£729.00
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Further Information

Additional Names:
PVR,FLJ25946,PVS,CD155,TAGE4,HVED,NECL5
Application Note:
This recombinant protein can be used for E, WB. For research use only.
Background:
CD155 (cluster of differentiation 155) also known as the poliovirus receptor is a protein that is encoded by the PVR gene. CD155 is a Type I transmembrane glycoprotein in the immunoglobulin superfamily. Commonly known as Poliovirus Receptor (PVR) due to its involvement in the cellular poliovirus infection in primates, CD155's normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. The role of CD155 in the immune system is unclear, though it may be involved in intestinal humoral immune responses. Subsequent data has also suggested that CD155 may also be used to positively select MHC-independent T cells in the thymus.
Background References:
  • Zhang P., et al., 2008, Proc. Natl. Acad. Sci., 105 (47): 18284-18289.
  • Maier MK., et al., 2007, European Journal of Immunology, 37 (8): 2214-2225.
  • He Y., et al., 2000, Proc. Natl. Acad. Sci., 97 (1): 79-84.
Biological Activity:
Measured by its binding ability in a functional ELISA. Immobilized Human TIGIT, Fc Tag at 2 ug/mL (100 uL/well) can bind Human CD155, mouse IgG2a Fc tag with a linear range of 0.98-7.81 ng/mL.
Buffer:
Tris?with?Glycine,?Arginine?and?NaCl,?pH7.5
Fusion Tag:
mouse IgG2a Fc tag
NCBI Gene ID #:
5817
NCBI Official Name:
poliovirus receptor isoform alpha precursor
NCBI Official Symbol:
CD155
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
62.2 kDa
Protein Accession #:
NP_006496.2
Purity:
>95% as determined by SDS-PAGE.

Endotoxin level is less than 0.1 EU per ug by the LAL method.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
P15151(340I/M)

Documents