Galectin-9 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-96-877-0.05mg | 0.05mg | £657.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
Galectin-9,LGALS9,Ecalectin
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Galectin-9 (LGALS9) is also known as tumor antigen HOM-HD-21 and ecalectin. Galectins are a family of proteins defined by their binding specificity for beta-galactoside sugars, such as N-acetyllactosamine (Galbeta1-3GlcNAc or Galbeta1-4GlcNAc), which can be bound to proteins by either N-linked or O-linked glycosylation. As for Galectin-9, it has high affinity for the Forssman pentasaccharide, and it is also the ligand for HAVCR2/TIM3. Forthermore, Galectin-9 stimulates bactericidal activity in infected macrophages by causing macrophage activation and IL1B secretion which restricts intracellular bacterial growth.
Background References:
- Tuereci O., et al., 1997, J. Biol. Chem. 272:6416-6422.
- Dai S.Y., et al.,2005, J. Immunol. 175:2974-2981.
Buffer:
20 mM MOPS, 50 mM NaCl, 1 mM EDTA, 2 mM DTT, pH7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
3965
NCBI Official Name:
galectin-9 isoform short
NCBI Official Symbol:
Galectin-9
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
36.6 kDa
Protein Accession #:
BAA31542
Purity:
>95% as determined by SDS-PAGE.
Endotoxin level is less than 1.0 EU per ug by the LAL method.
Endotoxin level is less than 1.0 EU per ug by the LAL method.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
BAA31542