ProSci

B7-H3 Recombinant Protein

Product Code:
 
PSI-96-974
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Western Blot (WB)
Storage:
 
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
 

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PSI-96-974-0.1mg0.1mg£686.00
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Further Information

Additional Names:
B7-H3,CD276,B7 homolog 3
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
B7 homolog 3 (B7-H3), a member of the immunoglobulin superfamily, is also known CD276, which contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domains. B7-H3 may participate in the regulation of T-cell-mediated immune response. B7-H3 also plays a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. Furthermore, B7-H3 is involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. It could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy.
Background References:
  • Chapoval A.I., et al., 2001, Nat. Immunol. 2:269-274.
  • Castriconi R., et al., 2004, Proc. Natl. Acad. Sci. U.S.A. 101:12640-12645.
  • Wang L., et al., 2005, Eur. J. Immunol. 35:428-438.
Buffer:
Tris?with?Glycine,?Arginine?and?NaCl,?pH7.5
Fusion Tag:
Fc Tag
NCBI Gene ID #:
102657
NCBI Official Name:
CD276 antigen precursor
NCBI Official Symbol:
B7-H3
NCBI Organism:
Mus musculus
Physical State:
Lyophilized
Predicted Molecular Weight:
50.1 kDa
Protein Accession #:
NP_598744
Purity:
>95% as determined by SDS-PAGE.

Endotoxin level is less than 1.0 EU per ug by the LAL method.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
Q8VE98

Documents