ProSci

DLL1 Recombinant Protein

Product Code:
 
PSI-96-862
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
 

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PSI-96-862-0.1mg0.1mg£597.00
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Further Information

Additional Names:
DLL1,Delta1,H-Delta-1
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Delta-like protein 1 (DLL1) is also known as Drosophila Delta homolog 1 (Delta1 or H-Delta-1), which contains one DSL domain and eight EGF-like domains. DLL1 is ubiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation. As for expression, DLL1 is expressed in heart and pancreas, with lower expression in brain and muscle and almost no expression in placenta, lung, liver and kidney. Furthermore, DLL1 acts as a ligand for Notch receptors. Also, DLL1 can block the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor.
Background References:
  • Han W., et al., 1999, Blood 95:1616-1625.
  • Gray G.E., et al., 1998, Am. J. Pathol. 154:785-794
  • Clark H.F., et al., 2002, Genome Res. 13:2265-2270.
Buffer:
50 mM Tris, 150 mM NaCl, pH 7.5
Fusion Tag:
His Tag
NCBI Gene ID #:
28514
NCBI Official Name:
delta-like protein 1 precursor
NCBI Official Symbol:
DLL1
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
58.4 kDa
Protein Accession #:
NP_005609
Purity:
>95% as determined by SDS-PAGE.

Endotoxin level is less than 1.0 EU per ug by the LAL method.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
O00548

Documents