anti-PD-1 (mouse) mAb (blocking) (1H10)
Product Code:
AG-20B-0075
Antibody Isotype:
Rat IgG2aκ
Antibody Clonality:
Monoclonal
Applications:- Fluorescence-activated cell sorting (FACS)
- Functional Study
No additional charges, what you see is what you pay! *
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available!
Contact us to find what you can save.
This product comes from:
Switzerland.
Typical lead time:
7-10 working days.
Contact us for more accurate information.
- Further Information
- Documents
- References
- Show All
Further Information
Alternate Names/Synonyms:
CD279; Programmed Cell Death Protein 1
1mg/ml
32160000
<0.01EU/µg purified protein (LAL test; Lonza).
liquid
Liquid. In PBS containing 0.02% sodium azide.
After opening, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.
Mouse PD-1 transfected cell line.
Monoclonal Antibody. Recognizes mouse PD-1 (CD279). Does not cross-react with human PD-1d. Isotype: Rat IgG2akappa. Clone: 1H10. Applications: FACS, FUNC (Blocking). Liquid. In PBS containing 0.02% sodium azide. CD279 (Programmed Cell Death Protein 1; PD-1) is a type I transmembrane protein belonging to the CD28/CTLA-4 family of immunoreceptors that mediate signals for regulating immune responses. Members of the CD28/CTLA-4 family have been shown to either promote T cell activation (CD28 and ICOS) or downregulate T cell activation (CTLA-4 and PD-1). CD279 is expressed on activated T cells, B cells, myeloid cells and on a subset of thymocytes. In vitro, ligation of CD279 inhibits TCR-mediated T cell proliferation and production of IL-1, IL-4, IL-10 and IFN-gamma. In addition, CD279 ligation also inhibits BCR mediated signaling. CD279 deficient mice have a defect in peripheral tolerance and spontaneously develop autoimmune diseases.
NP_005009.2
Plastic Vial
CD279 (Programmed Cell Death Protein 1; PD-1) is a type I transmembrane protein belonging to the CD28/CTLA-4 family of immunoreceptors that mediate signals for regulating immune responses. Members of the CD28/CTLA-4 family have been shown to either promote T cell activation (CD28 and ICOS) or downregulate T cell activation (CTLA-4 and PD-1). CD279 is expressed on activated T cells, B cells, myeloid cells and on a subset of thymocytes. In vitro, ligation of CD279 inhibits TCR-mediated T cell proliferation and production of IL-1, IL-4, IL-10 and IFN-gamma. In addition, CD279 ligation also inhibits BCR mediated signaling. CD279 deficient mice have a defect in peripheral tolerance and spontaneously develop autoimmune diseases.
>95% (SDS-PAGE)
Purified from concentrated hybridoma tissue culture supernatant.
Recognizes mouse PD-1 (CD279). Does not cross-react with human PD-1d.
Non-hazardous
Primary Antibodies
12352203
Stable for at least 1 year after receipt when stored at -20°C.