NSJ Bioreagents

BAFF Antibody

Product Code:
 
NSJ-R30618
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
After reconstitution, the BAFF antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
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Western blot testing of BAFF antibody and Lane 1: recombinant human protein 10ng; 2: 5ng; 3: 2.5ng~
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IHC-P: BAFF antibody testing of human tonsil tissue
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Western blot testing of BAFF antibody and Lane 1: recombinant human protein 10ng; 2: 5ng; 3: 2.5ng~
IHC-P: BAFF antibody testing of human tonsil tissue

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CodeSizePrice
NSJ-R30618-100ug100 ug£535.00
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Further Information

Application Details :
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the BAFF antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
The B cell activating factor BAFF (BlyS/TALL-1/zTNF4) is a tumor necrosis factor (TNF)-related ligand that promotes B cell survival and binds to three receptors (BCMA, TACI, and the recently described BAFFR). BAFF was regularly detected by enzyme-linked immunosorbent assay in brain tissue lysates and in normal spinal fluid, and in astrocytes by double fluorescence microscopy. It is localized in astrocytes close to BAFFR-expressing immune cells. BAFF receptors were strongly expressed in situ in primary central nervous system (CNS) lymphomas. The protein plays an important role in humoral immunity and in autoimmune diseases, including RA. Local gene targeting inhibited proinflammatory cytokine expression, suppressed generation of plasma cells and Th17 cells, and markedly ameliorated joint pathology.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Amino acids 265-285 (RENAQISLDGDVTFFGALKLL-human) were used as the immunogen for this BAFF antibody.
Limitation:
This BAFF antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse, Rat
Uniprot #:
Q9Y275