NSJ Bioreagents

FCGRT Antibody

Product Code:
 
NSJ-R32149
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
After reconstitution, the FCGRT antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
1 / 2
Western blot testing of human A549 cell lysate with FCGRT antibody. Expected/observed molecular weight ~51 kDa.~
2 / 2
IHC testing of FFPE human lung cancer tissue with FCGRT antibody. HIER: Boil the paraffin sections in pH 6, 10mM citrate buffer for 20
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Western blot testing of human A549 cell lysate with FCGRT antibody. Expected/observed molecular weight ~51 kDa.~
IHC testing of FFPE human lung cancer tissue with FCGRT antibody. HIER: Boil the paraffin sections in pH 6, 10mM citrate buffer for 20

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NSJ-R32149-100ug100 ug£535.00
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Further Information

Application Details :
Western blot: 0.1-0.5ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml
Application Note:
Optimal dilution of the FCGRT antibody should be determined by the researcher.
Description:
IgG receptor FcRn large subunit p51 is a protein that in humans is encoded by the FCGRT gene. This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. In addition, it is postulated that long-range cis inactivation of the FCGRT gene is responsible for hypercatabolism of IgG in myotonic dystrophy. The FCGRT gene is closely situated to the DMPK gene, which is mutant in DM.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Amino acids 56-291 of human FCGRT were used as the immunogen for the FCGRT antibody.
Limitation:
This FCGRT antibody is available for research use only.
Localization:
Cytoplasmic
Purity:
Antigen affinity
Species Reactivity :
Human
Uniprot #:
P55899