NSJ Bioreagents

TRAM2 Antibody

Product Code:
 
NSJ-R31118
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Storage:
 
After reconstitution, the TRAM2 antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
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Western blot testing of TRAM2 antbody; Lane 1: Recombinant mouse protein 10ng; 2: 5ng; 3: 2.5ng
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Western blot testing of TRAM2 antbody; Lane 1: Recombinant mouse protein 10ng; 2: 5ng; 3: 2.5ng

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NSJ-R31118-100ug100 ug£535.00
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Further Information

Application Details :
Western blot: 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the TRAM2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Translocation-Associating Membrane Protein 2, also called KIAA0057, is a protein that in humans is encoded by the TRAM2 gene. It is a component of the translocon, a gated macromolecular channel that controls the posttranslational processing of nascent secretory and membrane proteins at the endoplasmic reticulum(ER) membrane. By genomic sequence analysis, Onuchic et al.(1999) mapped the gene to chromosome 6p21.1-p12 near the PKHD1 gene. Upon activation, quiescent hepatic stellate cells proliferate, change morphologically into myofibroblasts, and increase their synthesis of extracellular matrix proteins. Stefanovic et al.(2004) demonstrated that both TRAM2 and collagen type I are upregulated in activated rat and human hepatic stellate cells.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
An amino acid sequence from the C-terminus of mouse Translocation-Associating Membrane Protein 2 (RFIHSQLRHWREYWKEQ) was used as the immunogen for this TRAM2 antibody (100% rat homology).
Limitation:
This TRAM2 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse, Rat
Uniprot #:
Q924Z5