LAG-3 (mouse):Fc (mouse) (rec.)
Product Code:
AG-40B-0039
No additional charges, what you see is what you pay! *
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available!
Contact us to find what you can save.
This product comes from:
Switzerland.
Typical lead time:
7-10 working days.
Contact us for more accurate information.
- Further Information
- Documents
- References
- Show All
Further Information
Alternate Names/Synonyms:
Lymphocyte Activation Gene-3; FDC Protein; CD223
Induces maturation of mouse dendritic cells in vitro. Induces CD4 and CD8 antigen-specific T cells responses when coinjected s.c. in mice, together with the antigen.
0.5 mg/ml
32160000
<0.01EU/µg purified protein (LAL test; Lonza).
liquid
Liquid. In PBS.
After opening, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.PBS containing at least 0.1% BSA should be used for further dilutions.
Protein. The sequence coding for the 4 extracellular Ig-like domains of mouse LAG-3 (D1-D4) is fused to the Fc portion of mouse IgG2a (hinge-CH2-CH3). Source: CHO cells. Endotoxin content: <0.01EU/µg purified protein (LAL test; Lonza). Liquid. In PBS. Binds to human and mouse MHC class II. Purity: >95% (SDS-PAGE). Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.
~180kDa (SPS-PAGE, nonreducing), ~80kDa (SPS-PAGE, reducing)
Q61790
Application: Flow Cytometry: Detection of MHC class II molecules in combination with fluorescently labeled antibodies to IgG2a. Uni-Prot link Q61790: LAG-3 (mouse) http://www.uniprot.org/uniprot/Q61790
Plastic Vial
Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.
>95% (SDS-PAGE)
The sequence coding for the 4 extracellular Ig-like domains of mouse LAG-3 (D1-D4) is fused to the Fc portion of mouse IgG2a (hinge-CH2-CH3).
CHO cells
Binds to human and mouse MHC class II.
Fc
Non-hazardous
Other Proteins
12352202
Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.