Documents
Posters
Neutralizing Cadherin-11 Humanized Antibody for Prostate and Breast Cancer
Allergies
Alzheimer's Disease
Apoptosis
Autophagy
Autophagy Poster and related products
Autophagy Poster and autophagy related products offered by ProSci Inc.
Cannibalism For survival: Is autophagic (Type II) cell death and essential mechanism in successful tumour suppression?
Cancer
Assessment of circulating tumor cells with a novel, filtration-based method, in a phase IIIb multicenter study for...
Background: The presence of circulating tumor cells (CTCs) has been shown to be of prognostic relevance for patients with early and advanced breast cancer (BC). The usefulness of CTC assessments depends on accurate cell counts and corresponding analysis of molecular targets. The aim of this sub study was to assess the feasibility of a novel, integrated CTC platform for automated cellular protein and nucleic acid analysis in a prospective multi-center study. The Authors use TransFix to stabilise samples for analysis.
Cell Culture
A novel culture medium ages keratinocytes without the need for pro-aging stimuli
A cell’s environment plays a dominant role in determining its behaviour, both in vivo and in vitro. The aging process in vivo is an excellent example of environmental changes altering cell function. Age-related loss of cell function is the result of a complex cascade of events...
Cholesterol
Epigenetics
Exosomes
ExoCap™ Ultracentrifugation/Storage Booster Poster
Poster Submitted by MBL International and JSR Life Sciences: The ultracentrifugation reagent for the high recovery ratio of exosome from cell culture supernatant and the storage reagent of exosome at 4 degree Celsius.
Flow Cytometry
Infilitration of CNS by Acute Leukaemia: Analysis of Fresh and TransFix Stabilised CSF
CSF samples were analysed within 2-6 hours of sampling or after 72 hours of storage at +4°C in Transfix.Transfix preserved light scatter and key antigen expression patterns to allow for analysis of diagnostic and follow up CSF specimens for patients with CSN infiltration.
Inter-laboratory Comparison of the TransFix/EDTA Vacuum Blood Collection Tube (TVT) with the 5 mL Cyto-Chex® BCT
This study aimed to assess the performance of the TransFix Vacuum Blood Collection Tube (TVT) and BCT devices across three clinical FC sites for their shared intended purpose of stabilizing lymphocytes for immunophenotyping via flow cytometry for up to 14 days.
Validating the use of TransFix to stabilise cerebrospinal fluid (CSF) for flow cytometry immunophenotyping of ha
This study aimed to validate TransFix as a means of stabilising leukocytes in CSF for up to 72 hours following lumbar puncture. Also, to validate antisera panels for TransFix treated CSF samples. Fresh CSF samples were split into two aliquots and analysed fresh or stabilised with TransFix/EDTA.
Immunology
Non-integrative lentiviral particles for immunotherapy
RNA delivery to drive tumoralantigen presentation in a safe and efficient way.
Predictive Immunotherapy Models: Overcoming the challenge of T cells gene transfer
Have you ever dreamt you could transduce 60% of naive and 90% of activated T lymphocytes ? No more sorting of your cells : adoptive immunotherapy made easier
Metabolism
Neuroscience
Parkinson's Disease
Platelets
Remote Platelet Function Testing Using Platelet P-Selectin as a Marker of Platelet Activation. Findings in Patients With Stroke
Poster presented by N Dovlatova(1,2), S Heptinstall(1,2), J May (1,2), P Bath(1,2) 1: University of Nottingham, Clinical Neuroscience, UK. 2: Platelet Solutions Ltd, UK
Remote Platelet Function Testing Using Platelet-Bound P-Selectin as a Marker of Platelet Activation
Poster presented by S. Heptinstall and colleagues from University of Nottingham, Clinical Neuroscience, UK and Platelet Solutions Ltd., UK
Proteins
Development of a Real-Time Homogeneous TR-FRET Ubiquitin Conjugation and Deconjugation Assay Platform
TR-FRET (Time Resolved Fluorescence Resonance Energy Transfer) uses the extended fluorescence emission decay lifetimes typical of rare-earth lanthanides to impart a short time-delay between FRET donor excitation and emission.
RNA
Efficient KO of PD1 in primary T cells using a new non-integrative lentiviral particle expressing CRISPR/Cas9 system
A CRISPR approach using LentiFlash™ RNA delivery leads to a highly efficient and dose-dependent knock-out in activated human T lymphocytes, without genomic integration
Stem Cells
Tetramers
Brilliant Violet (TM) Tetramers from MBLI Poster
Reducing background in MHC tetramer assays: Characterisation of a new commercially available MHC tetramer for the violet laser – Brilliant!
Metal-Conjugated NeutrAvidin for MHC Multimer Assays Using Mass Cytometry
Poster presented at AAI 2015. Describes the workflow for enumeration and identification of CMV-specific CD8+ T cells with NeutrAvidin metal reagent complexed with HLA-A*0201 CMV pp65 biotinylated monomer from MBL International (among other methods).
Rapid generation of new specificity MHC tetramers for the detection of antigen-specific T cells using a novel peptide exchange t
..etramer kit that allows for quantification of peptide exchange. Poster presented at the 31st Annual Meeting of the Society for Immunotherapy of Cancer 2016 by MBL International
The HLA-A*02:01 Quickswitch(TM) Quant kit can be used for determining the biological activity of a cancer vaccine
Poster presented at AAI, by MBL International
