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Showing 25 of 803 items meeting your criteria.

Type	Category	Supplier

Tumour-Associated Antigens of CAR T Cell Therapy Abnova provides a range of Tumour-Associated Antigens of CAR T Cell Therapy.
Documents	Cancer	Abnova Corporation	View
Innate Immunity: TNF-TRAF Signalling Abnova provides a range of antibodies for research into TNF-TRAF Signalling.
Documents	Immunology	Abnova Corporation	View
The Role of Tumour Necrosis Factor in Amyotrophic Lateral Sclerosis Abnova provides a range of reagents for research into the role of Tumour Necrosis Factor in Amyotrophic Lateral Sclerosis.
Documents	Neuroscience	Abnova Corporation	View
TDAR Immunotoxicity ELISA Kits T-cell-dependent antibody response (TDAR) to an antigen is a gold standard in vivo assessment of immunotoxicity at the preclinical stage of drug discovery. Abnova offers a wide variety of ELISA kits for biomarkers used in TDAR assays.
Documents	ELISA	Abnova Corporation	View
Targeting EGFR in Lung Cancer Approximately there are 10% of patients with NSCLC in the US and 35% in Asia harboring EGFR mutations. EGFR mutations occur within exons 18–21 encoding a portion of the EGFR kinase domain. These mutations affect the kinase activity of EGFR, leading to downstream pro-survival signaling pathways. EGFR mutations confer sensitivity of EGFR TKI and as well as are involved in mechanisms of acquired resistance to EGFR TKI therapy. Resistance can occur through secondary resistance mutations (such as T790M) occurring in the ATP-binding domain.
Documents	Cancer	Abnova Corporation	View
Targeting BRAF in Human Cancer Also known as NS7; B-raf; BRAF1; RAFB1; B-RAF1, is a member of the RAF family of serine/threonine protein kinases activating the MAP kinase/ERK-signaling pathway and normally involved in regulating cell differentiation, proliferation, growth, and apoptosis. BRAF V600E mutation drives tumor growth by hyperactivating the extracellular signal regulated kinase (ERK) signaling pathway in the absence of any extracellular stimuli.
Documents	Cancer	Abnova Corporation	View
Signalling Pathways Involved in T Cell Exhaustion in TME Exhausted T cells have been identified to accumulate in tumour microenvironment (TME) and fail to eliminate cancer cells. The exhaustion is characterised by the expression of multiple inhibitory molecules, including PD-1 and CTLA4. PD-1/PD-L1 signaling antagonises TCR signaling and induces the transcription of exhaustion-related genes. Both PD-1/PD-L1 and CTLA4 signaling inhibit the pathways that promote cell cycle arrest in T cells. The inhibition of PI3K/Akt/mTOR pathway mediated by PD-1/PD-L1 or CTLA4 also leads to decreases in glycolysis and amino acid metabolism and suppresses mitochondrial biogenesis. These exhaustion-related changes result in dysfunctional T cells, which are obstacles to effective tumour immunotherapy.
Documents	Cancer	Abnova Corporation	View
SARS-CoV-2 S Neutralising Antibodies Neutralising antibodies are able to block the interaction between viruses and host cells, which can potentially stop the infection. Abnova has developed a group of SARS-CoV-2 S monoclonal antibodies, which are neutralising mouse monoclonal antibodies targeting recombinant SARS-CoV-2 spike protein.
Documents	COVID-19	Abnova Corporation	View
Renal Cell Carcinoma Antibodies Abnova provides a range of antibodies specific for renal cell carcinomas.
Documents	Cancer	Abnova Corporation	View
Recombinant Antibodies Abnova provides a selection of Recombinant Monoclonal Antibodies.
Documents	Antibodies	Abnova Corporation	View
Prostate cancer biomarkers Abnova provides a range of biomarkers specifically for prostate cancer.
Documents	Cancer	Abnova Corporation	View
Precipitor 32 Plus Abnovas Precipitor™ 32 Plus system is an automated magnetic bead platform for high throughput extraction, purification, and precipitation. Combining 96 deep well plates with conjugated magnetic beads, Precipitor™ 32 Plus easily handles 32 different assays simultaneously by transferring beads from one well to the next for mixing, binding, washing, and elution reactions via the robotic action of parallel magnetic rods.
Documents	Beads	Abnova Corporation	View
Pancreatic Cancer Antibodies Abnova provides antibodies specifically for pancreatic cancer.
Documents	Cancer	Abnova Corporation	View
NSCLC Antibodies Abnova provides a range of Non-Small Cell Lung Cancer Antibodies.
Documents	Cancer	Abnova Corporation	View
miRNA Probes Abnova has developed numerous DIG-labelled miRNA probes suitable for formalin-fixed, paraffin-embedded (FFPE) tissues, enabling you to assay multiple targets and visualise colocalised signals in specimens.
Documents	miRNA	Abnova Corporation	View
Metabolic Regulations in T Cells Abnova provides a range of products for Metabolic Regulations in T Cells.
Documents	Immunology	Abnova Corporation	View
Metabolic Processes Regulating Ferroptosis General processes for regulating ferroptosis are associated with iron, lipid, and amino acid metabolism.
Documents	Cell Cycle	Abnova Corporation	View
Melanoma Antibodies Abnova provides a range of antibodies specifically for melanomas.
Documents	Cancer	Abnova Corporation	View
Macrophage & myeloid DC Abnova provides a range of Macrophage & Dendritic Cell Biomarkers.
Documents	Immunology	Abnova Corporation	View
Leukocyte biomarkers Abnova provides a range of leukocyte biomarker antibodies.
Documents	Antibodies	Abnova Corporation	View
Influence of HIFs on Tumour Microenvironment HIFs induce the expression of integrins. The integrins connect the ECM to the cytoskeleton and form focal adhesion, which enhances the cancer cell motility and invasion capacity. HIFs can also trigger collagen production and regulate the expression of collagen-modifying enzymes. The hypoxia-induced collagen deposition might potentiate cancer metastasis.
Documents	Cancer	Abnova Corporation	View
Infectious Disease Rapid Tests Infectious disease rapid tests enable the simultaneous detection of multiple markers in serum, plasma, cerebrospinal, and synovial fluid. They are an important tool for the differential study of diseases with similar symptoms. They are used for the confirmation of borderline or positive ELISA.
Documents	Immunology	Abnova Corporation	View
Immune Checkpoint Receptors Abnova Corporation provides a range of Immune Checkpoint Receptors.
Documents	Immunology	Abnova Corporation	View
Histone Antibodies and Kits Abnova provides a range of Histone antibodies and kits.
Documents	Antibodies	Abnova Corporation	View
FISH Clinical Applications Abnova provides a range of FISH probes for clinical applications.
Documents	Probes	Abnova Corporation	View

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