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Enterovirus 71(EV71), a non-enveloped and icosahedral single-stranded RNA virus, belongs to family Picornaviridae, genus Enterovirus, species Human Enterovirus A (HEV-A). It is one of the major etiological agents causing hand, foot, and mouth disease (HFMD), which generally affects infants and young children. In addition to HFMD, EV71 epidemic has resulted in many fatalities because of serious neurological complications and has been identified as a serious threat to public health. Abnova has developed high quality Human Enterovirus 71 Antigen ELISA Kit for the qualitative detection of Human Enterovirus 71 Antigen in serum, plasma, cell culture supernatants, cell lysates, tissue homogenates.
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Virology
Abnova Corporation
Elabscience have developed a series of Metabolism Assay Kits to meet the requirements of researchers, yielding efficient detection of biochemical indicators.
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Metabolism
Elabscience
Contents: ELISA Kits Characteristic Advantages, Why Choose Elabscience® ELISA Kits, MS ELISA Kit Product Features, QuicKey Pro™ ELISA Kit Product Features, Top-30 Selling ELISA Kits, and High IF Literature.
Documents
ELISA
Elabscience
YAP1 encodes the human ortholog of chicken YAP protein which binds to the SH3 domain of the Yes proto-oncogene product. This protein contains a WW domain that is found in various structural, regulatory and signaling molecules in yeast, nematode, and mammals, and may be involved in protein-protein interaction.
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Antibodies
Abnova Corporation
SQSTM1 encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
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Antibodies
Abnova Corporation
High purity, Animal free, Quality assured, Cost-effective, Save more with bulk order. Abnova, March 2023
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Proteins
Abnova Corporation
High purity, Animal free, Quality assured, Cost-effective, Save more with bulk order. Popular Recombinant & Native Proteins from Abnova, April 2023
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Proteins
Abnova Corporation
MIF encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways.
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Antibodies
Abnova Corporation
Datasheet for product P0001015
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Datasheets
AddexBio
Cloud-Clone Active proteins based on GMP level development, can provide a variety of specifications of protein, to meet the needs of basic science experiments, drug screening, animal drug delivery and other experiments. High Purity, Multi-species, Multi-specifications, Multi-detections
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Proteins
Cloud-Clone Corp.
After 14 years of development and technology accumulation, Cloud-Clone has developed ELISA kit and CLIA kit based on enzyme linked immunoassay technology. 8,000+ kinds of high quality assay kits covering 2,000+ indicators and 10+ species are designed to assist your experimental research. Includes Sandwich ELISA Kit, Competition ELISA Kit, CLIA Kit, Antibody ELISA, Mini ELISA, Instant ELISA, High-sensitive ELISA, Wide-range ELISA.
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ELISA
Cloud-Clone Corp.
How do you operate ELISA kits and get a satisfactory test result? What precautions should be paid attention to? Check this video recorded in ELK Biotechnologys lab!
Videos
ELISA
ELK Biotechnology
ELISA experiment operation video
Videos
ELISA
ELK Biotechnology
ELK Biotechnology CO., LTD is manufacturer of ELISA kits, Molecular biology products and Antibodies.
Videos
ELK Biotechnology
Through structural analysis and screening of 2342 marketed drugs and 1487 clinical phase drugs, TargetMol has constructed a Drug-Fragment Library consisting of 1159 fragments.
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Small Molecules
TargetMol
A broad and diverse herbal source is an important guarantee for a high-quality Natural Product Library. TargetMol has collected massive relevant information of nearly 10,000 natural product monomers and numerous plants in 196 families, 887 genera. We can be a great help for you to search your desired compounds according to plant classifications.
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Small Molecules
TargetMol
List of compound libraries available with TargetMol
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Small Molecules
TargetMol
Documents
TargetMol
Products & Services: Compound Libraries, Inhibitors & Agonists, Reagent Kits, Compound Synthesis, CADD and Recombinant Proteins.
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Supplier Introduction
TargetMol
Drug repurposing, also known as the new use of old drugs, is a strategic approach to discover new applications for old or investigational drugs beyond their original approved applications. While the development of new drugs is a process with a high failure rate, high cost, and slow pace, repositioning old drugs for common and rare diseases is becoming increasingly attractive because of the advantages of low R&D costs and short development time.
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Small Molecules
TargetMol
The Cell Counting Kit-8 (CCK-8) utilizes the water-soluble tetrazolium salt, WST-8, to achieve rapid detection. The principle is that WST-8 can be reduced by dehydrogenases in the mitochondria to form an orange-yellow formazan in the presence of an electron coupling reagent. Through colorimetry, the number of viable cells can be dynamically quantified, thereby enabling the detection of cell proliferation or drug toxicity. The CCK-8 can be directly added to cells without the need for pre-mixing with other components, making the testing process convenient with accurate results.
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Cell Based Assays
TargetMol
Primary PBMCs from Cell Generation are isolated directly from peripheral blood of eligible donors via leukapheresis procedure. Leukapheresis performed following Institutional Review Board (IRB) consented healthy or diseased human donors.
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Biological Samples
Cell Generation
IDH1/2 Mutations
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Cancer
Abnova Corporation
Androgen receptor (AR) is a member of the steroid receptor transcription factor family. In prostate cancer, increased levels of androgens in the tumor cells promote (1) AR signaling associated with cell-cycle regulation, growth, and survival, and (2) the expression of oncogenic fusion genes. AR-V7 is one of the splice variants of AR lacking the C-terminal LBD, but being constitutively active as a transcription factor and capable of promoting activation of target genes.
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Cancer
Abnova Corporation
Inactive monomeric heat shock factor 1 (HSF1) exists predominantly in the cytoplasm and remains repressed by complex with regulatory proteins of HSF1 its own transcriptional targets of heat-shock protein (HSP) and cytosolic chaperonin TCP1 ring complex (TRiC). Upon a wide range of stress conditions, HSF1 is activated to undergo trimerization, nuclear translocation, and post-translational modifications (PTMs) including phosphorylation, acetylation, and sumoylation, converted into a DNA-binding-competent, active homotrimer. HSF1 is then modified by different inhibitory PTMs to cause DNA dissociation, HSF1 inactivation, and HSF1 recycling/degradation and maintained in a negative-feedback mechanism.
Documents
Antibodies
Abnova Corporation