anti-Acrolein [ACR], mAb (5F6)

JaICA
Product Code: JAI-MAR-020N
Product Group: Primary Antibodies
Supplier: JaICA

CodeSizePrice
JAI-MAR-020N-20ug20 ug£490.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Antibody Isotype: Mouse IgG1kappa
Antibody Clonality: Monoclonal
Antibody Clone: 5F6
Regulatory Status: RUO
Target Species: Human
Application: Immunohistochemistry (IHC)
Shipping:
BLUE ICE
Storage:
-20°C

Further Information

EClass:
32160000
Form (Short):
liquid
Formulation:
Frozen liquid. Contains 10mM PBS, 0.1% NaN3 and 0.5% BSA.
Handling Advice:
Avoid freeze/thaw cycles.
Immunogen:
ACR-modified keyhole-lympet hemocyanine.
Long Description:
Monoclonal Antibody. Recognizes ACR-modified proteins (especially FDP-lysine type derivatives). Frozen liquid. Contains 10mM PBS, 0.1% NaN3 and 0.5% BSA. Acrolein (ACR) is a representative carcinogenic aldehyde found ubiquitously in the environment and formed endogenously through oxidation reactions, such as lipid peroxidation and myeloperoxidasecatalyzed amino acid oxidation. ACR is highly reactive aldehyde and reacts with lysine residue in protein. The reaction with ACR and lysine residue leads to the formation of numerous numbers of adducts, such as formyl-dehydropiperidino-lysine (FDP-lysine) type derivative.
Package Type:
Plastic Vial
Product Description:
Acrolein (ACR) is a representative carcinogenic aldehyde found ubiquitously in the environment and formed endogenously through oxidation reactions, such as lipid peroxidation and myeloperoxidasecatalyzed amino acid oxidation. ACR is highly reactive aldehyde and reacts with lysine residue in protein. The reaction with ACR and lysine residue leads to the formation of numerous numbers of adducts, such as formyl-dehydropiperidino-lysine (FDP-lysine) type derivative.
Specificity:
Recognizes ACR-modified proteins (especially FDP-lysine type derivatives).
Transportation:
Non-hazardous
UNSPSC Category:
Primary Antibodies
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 3 years after receipt when stored at -20°C.

References

Protein-bound acrolein: Potential markers for oxidativestress: K. Uchida, et al.; PNAS 95, 4882 (1998) | Protein-bound acrolein: A novel markers of oxidativestress in Alzheimer's Disease: Y. Noel, et al.; J. Neurochem. 72, 751 (1999)

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