UK and Ireland Distributor of MBL International - Antibodies, Assay Kits, Tetramers and Reagents for Life Science Research and Clinical Diagnostics

MBL

Established in 1993, MBL International Corporation (MBLI) is a leading life science company focused on providing high quality, innovative, solutions-based products for both life science research and clinical diagnostics. Their products are used widely in academic research institutions, pharmaceutical and biotechnology companies, government agencies as well as hospital and reference laboratories.

The MBLI product range can be divided into five distinct categories:

Life Science Research

General Reagents

MBLI develops, manufactures, and markets a broad portfolio of monoclonal and polyclonal antibodies, fluorescent and recombinant proteins and ELISA kits for research related to allergy, apoptosis, autophagy, cancer, epigenetics, immunology, and neuroscience.

Read More

MHC Tetramers: Directly Measure Antigen-Specific T Cells

MBLI has a wide portfolio of immune monitoring research products including tetramer technology for vaccine development, rapid T-cell detection and quantification in the pharmaceutical industry or bioresearch industry.

Read More

Drug Discovery Tools

MBL International Corporation offers fluorescent protein-based drug discovery tools for use in living cells. Their novel technology, Fluoppi, can visualise Protein-Protein Interaction (PPI) of interest in living cells. Moreover, other product offering such as Keima-Red and FUCCI, can visualise autophagy/mitophagy and cell cycle respectively. These technologies are applicable for cell-based high-throughput drug screening.

Read More

Clinical Diagnostics

Detection of Autoimmune Diseases

Autoimmune diseases are classified into systemic autoimmune disease and organ-specific autoimmune disease. MBLI offers a wide variety of ELISA and immunofluorescence assays (IFA) for the detection of disease-related autoantibodies including anti-nuclear antibodies and anti-desmosomal structural protein antibodies.

Read More

Blog posts

Streamline the detection of CD4 T cells with QuickSwitch™ Class II Quant Tetramer Kits

Use QuickSwitch™ Class II Quant Tetramer to investigate peptide-MHC binding affinities & conclude with your specialised CD4+ T cell detection reagent!

More

The Importance of In Vivo Isotype Controls in Advancing Therapeutic Drug Development

MBLI offer a webinar that addresses the FAQs they receive from researchers. They have also included information to assist in designing in vivo studies.

More

Protective Role of Invariant Natural Killer T (iNKT) cells 

CD1d, non-classical MHC molecules, present phospholipid & glycosphingolipid antigens to iNKT cells. MBL tetramers help measure CD1d positive NKT cells

More

Introducing MBLI's easy-to-use Western Reagents

MBL Western Substrates are highly sensitive & compatible chemiluminescent substrates for use with immunoblots with HRP-conjugated secondary antibodies

More

2023 Advancements in Research with QuickSwitch™ Custom Tetramer Kits

Here are the highlights of some of the influential publications that have utilised MBLI QuickSwitch™ Tetramer Kits in 2023.

More

Respiratory Syncytial Virus (RSV): Continued Research for the Most Prevalent Respiratory Virus Among Children

RSV is a significant respiratory virus in young children, & is the primary cause of hospitalisations, particularly bronchiolitis & pneumonia.

More

Advancements in the understanding of m7G Modification

There is more data that highlights the significant role of m7G modification in human diseases, particularly cancer.

More

New Innovative Product: Human R-spondin 1: Organoid Culture

MBL have a new innovative product available: Human R-spondin 1, for use in organoid culture.

More

The Impact of In Vivo Isotype Controls on Therapeutic Drug Development

In vivo antibody studies offer a wide range of applications. Discover the significant impact of antibody selection on your experiment.

More

Beyond cholesterol metabolism: The pleiotropic effects of (PCSK9)

MBL International is at the forefront of providing PCSK9 assay kits and reagents to support the advancement of PCSK9 studies.

More

What Exactly is a TCR Tetramer?

A TCR Tetramer is a reagent prepared by tetramerising biotinylated antigen-specific TCRs with the help of phycobiliprotein-labelled streptavidin.

More

Explore the Limitless Potential of IL-18

Researchers take advantage of MBL International's recombinant IL-18 to activate varying cells like peripheral blood cells, macrophages, NK cells and T cells to identify targets.

More

The invaluable role of QuickSwitch™ kits in validating predicted results

Wang, Wenfeng, et al 2023, selected the top 15 top peptides for self-antigen for their study. By using the QuickSwitch™ kit, they successfully switched 6 peptides to the tetramer complex with an efficiency of over 75%.

More

Caspase Activity: Essential for Apoptosis

MBLI 's APOPCYTO Caspase-3,8,9 Colorimetric Assay Kit detects caspase activity in cell extract with LEHD-pNA as a substrate, in which LEHD sequence is recognised by each active caspase selectively.

More

Ensure Accurate Immune Monitoring Results with Negative Controls

Negative controls aid precision of immune response monitoring. For HLA-A*02:01 alleles, MBLI offers a “Negative Tetramer” in BV421, PE or APC.

More

Visualising Protein-Protein Interaction with FLUOPPI Technology

MBLI's innovative technology, Fluoppi, simplifies the visualisation of protein-protein interaction.

More

Documents

  Category Title  
Show more...

No more documents to display.