UK and Ireland Distributor of MBL International - Antibodies, Assay Kits, Tetramers and Reagents for Life Science Research and Clinical Diagnostics

MBL

Established in 1993, MBL International Corporation (MBLI) is a leading life science company focused on providing high quality, innovative, solutions-based products for both life science research and clinical diagnostics. Their products are used widely in academic research institutions, pharmaceutical and biotechnology companies, government agencies as well as hospital and reference laboratories.

The MBLI product range can be divided into five distinct categories:

Life Science Research

General Reagents

MBLI develops, manufactures, and markets a broad portfolio of monoclonal and polyclonal antibodies, fluorescent and recombinant proteins and ELISA kits for research related to allergy, apoptosis, autophagy, cancer, epigenetics, immunology, and neuroscience.

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MHC Tetramers: Directly Measure Antigen-Specific T Cells

MBLI has a wide portfolio of immune monitoring research products including tetramer technology for vaccine development, rapid T-cell detection and quantification in the pharmaceutical industry or bioresearch industry.

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Drug Discovery Tools

MBL International Corporation offers fluorescent protein-based drug discovery tools for use in living cells. Their novel technology, Fluoppi, can visualise Protein-Protein Interaction (PPI) of interest in living cells. Moreover, other product offering such as Keima-Red and FUCCI, can visualise autophagy/mitophagy and cell cycle respectively. These technologies are applicable for cell-based high-throughput drug screening.

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Clinical Diagnostics

Detection of Autoimmune Diseases

Autoimmune diseases are classified into systemic autoimmune disease and organ-specific autoimmune disease. MBLI offers a wide variety of ELISA and immunofluorescence assays (IFA) for the detection of disease-related autoantibodies including anti-nuclear antibodies and anti-desmosomal structural protein antibodies.

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Blog posts

FGF-Max: A Key Growth Factor in Organoid Culture

FGF-Max - a recombinant chimeric protein with features of both FGF-1 and FGF-2

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What are the Differences Between Organoids and Spheroids?

In general, there are two major differences: nature of the driving force for development and length of time 3D cultures can be maintained.

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Smart IP: Fast and Effective IP

Smart-IP is a line of highly specific tag antibodies conjugated to magnetic beads or magnetic agarose beads designed for faster immunoprecipitation.

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Knockout [KO] Validated Antibodies

MBLI introduces Knockout (KO) validation as the standard of antibody confirmation. KO validation is a highly effective technique that confirms the specificity of the antibody as depicted.

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LC3

The mammalian homologue of Atg8, LC3, is the most actively studied and frequently used as a mammalian autophagy marker.

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MESACUP™ anti-MDA5 TEST

Biomarker of dermatomyositis with rapidly progressive interstitial lung disease Clinically amyopathic dermatomyositis (CADM), dermatomyositis…

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Atg12 Binding Cascade: Cross-talk Between Apoptosis and Autophagy

MBLI's autophagy reagents include important targets such as LC3, p62/SQSTM1, ATG12, ATG14, ATG16L, ATG9, ULK1, and more.

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Why is the MHC monomer the ideal choice for your experimental design?

The MHC Monomer is a sub-component of an MHC Tetramer. Biotinylated Monomers are available for most associated Tetramer products.

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Flexibility and Expansion with BV421 Tetramers

Adding another marker to a flow cytometry panel can present a challenge when trying to accommodate all markers of interest in one panel. However, there is a solution.

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AMP-activated protein kinase (AMPK) Role in Cancer and Metabolic Diseases

MBL International’s AMPK kinase assay kit can be used to measure the activity of AMPK, a cellular energy sensor.

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QuickSwitch™ Quant Analysis of SARS-CoV-2 mRNA Vaccinations

MBL International provides QuickSwitch™ Tetramers for the Quant Analysis of SARS-CoV-2 mRNA Vaccinations.

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Cervical cancer is the fourth most common cancer affecting women: Antigen-Specific Detection of HPV and HSV 

Cervical cancer is the 4th most prevalent cancer among women, and the 7th most common cancer. MBLI provides HPV-related tetramers for use in research.

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Apoptosis - Roadway to Pathogenesis and Treatment

MBL International offers antibodies, recombinant proteins, kits and assays to assist in the detection and analysis of different apoptotic molecules.

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Rapid and Reliable Custom Tetramer Generation for T-Cell Staining

MBLI QuickSwitch™ kit technology aims to replicate the immune response by mimicking peptide exchange on an MHC molecule.

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HA-tags: Better Understanding of Localisation, Expression and Purification of Target Proteins

MBLI offers antibodies & kits for epitope tag experiments. These products provide high sensitivity for purification experiments & other applications.

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Defined Immune Response Tracking in Mice: OVA MHC Tetramers

T cell-dependent OVA antigen is used as a model protein for studying antigen-specific immune responses in mice. MBL has OVA related tetramer products.

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