CycLex SIRT6 Deacetylase Fluorometric Assay Kit Ver.2

1. North, B.J., and Verdin, E.; Sirtuins: SIRT6-related NAD-dependent protein deacetylases. Genome Biol. 5: 224, 2004 2. Michishita E et al.; Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins. Mol Biol Cell. 16: 4623, 2005 3. Mostoslavsky R et al.; Genomic instability and aging-like phenotype in the absence of mammalian SIRT6. Cell. 124: 315, 2006 4. Michishita E et al.; SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin. Nature. 452: 492, 2008 5. Yang B et al.; The sirtuin SIRT6 deacetylates H3 K56Ac in vivo to promote genomic stability. Cell Cycle. 8: 2662, 2009 6. Kawahara TL et al.; SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span. Cell. 136: 62, 2009 7. Van Gool F, et al.; Intracellular NAD levels regulate tumor necrosis factor protein synthesis in a sirtuin-dependent manner. Nat Med. 15: 206, 2009