Medical & Biological Laboratories (MBL)

CycLex CK2(Casein kinase II) Kinase Assay/Inhibitor Screening Kit

Product Code:
 
MBL-CY-1170
Regulatory Status:
 
RUO
Shipping:
 
2-8°C
Storage:
 
4°C
 

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MBL-CY-117096 Assays£601.00
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This product comes from: Japan.
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References

1. Lozeman, F.J., Litchfield, D.W., Piening, C., Takio, K., Walsh, K.A. and Krebs, E.G. (1990) Isolation and characterization of human cDNA clones encoding the ? and ?? subunits of CK2. Biochemistry 29, 8436?8447 2. Litchfield, D.W., Lozeman, F.J., Piening, C., Sommercorn, J., Takio, K., Walsh, K.A. and Krebs, E.G. (1990) Subunit structure of CK2 from bovine testis: demonstration that the ? and ?? subunits are distinct polypeptides. J. Biol. Chem. 265, 7638?7644 3. Maridor, G., Park, W., Krek, W. and Nigg, E.A. (1991) CK2. cDNA sequences, developmental expression and tissue distribution of mRNAs for ?, ?? and ? subunits of the chicken enzyme. J. Biol. Chem. 266, 2362?2368 4. Munstermann, U., Fritz, G., Seitz, G., Lu, Y.P., Schneider, H.R. and Issinger, O.-G. (1990) CK2 is elevated in solid human tumors and rapidly proliferating non-neoplastic tissue. Eur. J. Biochem. 189, 251?257 5. Pepperkok, R., Lorenz, P., Ansorge, W. and Pyerin, W. (1994) CK2 is required for transition of G0/G1, early G1, and G1/S phases of the cell cycle. J. Biol. Chem. 269, 6986?6991 6. Landesman-Bollag, E., Romieu-Mourez, R., Song, D.H., Sonenshein, G.E., Cardiff, R.D. and Seldin, D.C. (2001) Protein kinase CK2 in mammary gland tumorigenesis. Oncogene 20, 3247?3257 7. Seldin, D.C. and Leder, P. (1995) CK2 alpha transgene-induce murine lymphoma: relation to theileriosis in cattle. Science 267, 894?897 8. Landesman-Bollag, E., Channavajhala, P.L., Cardiff, R.D. and Seldin, D.C. (1998) p53 deficiency and mis-expression of protein kinase CK2a collaborate in the development of thymic lymphomas in mice. Oncogene 16, 2965?2974 9. Channavajhala, P. and Seldin, D.C. (2002) Functional interaction of protein kinase CK2 and c-Myc in lymphomagenesis. Oncogene 21, 5280?5288 10. Sayed, M., Pelech, S., Wong, C., Marotta, A. and Salh, B. (2001) Protein kinase CK2 is involved in G2 arrest and apoptosis following spindle damage in epithelial cells. Oncogene 20, 6994?7005 11. Desagher, S., Osen-Sand, A., Montessuit, S., Magnenat, E., Vilbois, F., Hochmann, A., Journot, L., Antonsson, B. and Martinou, J.C. (2001) Phosphorylation of bid by casein kinases I and II regulates its cleavage by caspase 8. Mol. Cell 8, 601?611 12. Li, P., Li, J., Muller, E., Otto, A., Dietz, R. and von Harsdorf, R. (2002) Phosphorylation by protein kinase CK2. A signaling switch for the caspase-inhibiting protein ARC. Mol. Cell 10, 247?258 13. Wang, H., Davis, A., Yu, S. and Ahmed, K. (2001) Response of cancer cells to molecular interruption of the CK2 signal. Mol. Cell. Biochem. 227, 167?174