Applied Biological Materials (abm)

Acral Lentiginous Melanoma Cell Line (MM011/LND1)

Product Code:
ABM-T8081
Product Group:
Cell Lines
Host Type:
Human
Regulatory Status:
RUO
 

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Further Information

Description:
This melanoma cell line panel is unique from all other available melanoma cell lines as these cells have been raised under conditions that prevent phenotype switching. MM011 is applicable for high-throughput screening/Drug testing and 3D cell cultures. MM011/LND1 is tumorigenic: cells produce xenograft tumors when injected into immunocompromised mice. Note: This cell line should be cited in a scientific publication as: MM011/LND1. Additional cell lines from this panel:Cat. T8080 - Acral Lentiginous Melanoma Cell Line (HBL (MM001))Cat. T8081 - Acral Lentiginous Melanoma Cell Line (MM011/LND1)Cat. T8082 - Lymph Node Metastasis SS Melanoma Cell Line (MM029)Cat. T8083 - Bladder Metastasis Nodular Melanoma Cell Line (MM031)Cat. T8084 - Lymph Node Metastasis Melanoma Cell Line (MM034)Cat. T8085 - Superficial Spreading Melanoma Cell Line (MM052)Cat. T8086 - Lymph Node Metastasis Melanoma Cell Line (MM057)Cat. T8087 - Lymph Node Metastasis SS Melanoma Cell Line (MM074)Cat. T8088 - Lymph Node Metastasis SS Melanoma Cell Line (MM165)
Donor History:
Derived from a lymph node metastasis of a female with Acral lentiginous melanoma (ALM)
Growth Conditions:
PriCoat™ T25 Flasks (G299) or Applied Cell Extracellular Matrix (G422) are recommended for optimal cell culture. Ham's F10 Medium + 10% FBS + 2 mM L-Glutamine (G275) + 1% Penicillin/Streptomycin Solution (G255), 37.0°C, 5% CO2.
Growth Properties:
Adherent, epithelial
Markers:
WT( BRAF, PTEN, P53, MET), NRAS(Q61K), C-KIT(Amp)
Population Doubling:
48-72
Split Ratio:
1:3 to 1:6
Tissue:
Lymph Node