Applied Biological Materials (abm)

Immortalized Human Mesothelial Cells (HPV E6E7)

Product Code:
 
ABM-T0456
Product Group:
 
Cell Lines
Host Type:
 
Human
Regulatory Status:
 
RUO
 

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CodeSizePrice
ABM-T04561x10^6 cells / 1.0 mlEnquire
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Further Information

Description:
The Immortalized Human Mesothelial cells - HPV E6/E7 are derived from the normal human mesothelium, an important structure lining human abdomen cavities to provide lubrication, transportation and movement of fluids, immune cells, cytokines and proteins. These specialized cells are critical in regulating inflammatory responses and innate immune systems to protect against infections and tumor propagation. Their roles in cancer metastasis, metabolic diseases, peritoneal dialysis and surgical adhesions make them an ideal model for cancer research, pathological and/or therapeutic study.
Donor History:
Not disclosed
Growth Conditions:
Use of PriCoat™ T25 Flasks (G299) or Applied Cell Extracellular Matrix (G422) is required for cell adhesion to the culture vessels. PriGrow I (TM001) + 10% FBS + 50 ng/ml rhEGF (Z100139) + 1% Penicillin/Streptomycin Solution (G255), 37.0°C, 5% CO2
Growth Properties:
Adherent, polygonal
Immortalisation Method:
Serial passaging and transduction with recombinant lentiviruses carrying HPV E6/E7 gene
Markers:
APOBEC3, CD105, VEGF
Population Doubling:
45 - 65
Seeding Density (/cm^2):
10,000 - 20,000
Tissue:
Peritoneum