Applied Biological Materials (abm)

Immortalized Human Hair Follicle Dermal Papilla Cells - HPV E6/E7

Product Code:
 
ABM-T0505
Product Group:
 
Cell Lines
Host Type:
 
Human
Regulatory Status:
 
RUO
 

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CodeSizePrice
ABM-T05051x10^6 cells / 1.0 mlEnquire
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Further Information

Description:
Human Hair Follicle Dermal Papilla cells are highly active mesenchymal cells isolated from the hair papilla embedded in extracellular matrix of scalp hair follicles. Dermal Papilla Cells play a significant role in controlling the hair growth cycle and production by involving in the epithelial-mesenchymal interaction of hair follicle cells. Their survival is regulated by signal transduction pathways such as ERK and Akt. These cells can be used for development and evaluation of hair growth products and identifying cell populations within the hair follicle. In addition, they can be used for in vitro screening of androgen blocking reagents since they have androgen receptors. Real Time PCR was used to quantify HPV E6 and E7 gene expression in immortalized cell line.
Donor History:
Not disclosed
Growth Conditions:
Use of PriCoat™ T25 Flasks (G299) or Applied Cell Extracellular Matrix (G422) is required for cell adhesion to the culture vessels. Prigrow X Series Medium (TM0505), 37.0°C, 5% CO2
Growth Properties:
Adherent, multipolar
Immortalisation Method:
Serial passaging and transduction with recombinant lentiviruses carrying HPV E6/E7 gene
Population Doubling:
24 - 48
Seeding Density (/cm^2):
20,000 - 30,000
Tissue:
Hair Follicle