AdipoGen Life Sciences

UNC5B (human):Fc (human)(rec.) (MultiPack)

Product Code:
AG-40B-0037
Product Group:
Recombinant Proteins
Host Type:
HEK 293 cells
Regulatory Status:
RUO
Target Species:
  • Human
  • Mouse
Shipping:
Blue Ice
Storage:
Short term: +4°C. Long term: -20°C
 

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This product comes from: Switzerland.
Typical lead time: 7-10 working days.
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Further Information

Alternate Names/Synonyms:
Netrin Receptor UNC5B; UNC5H2; Protein Unc-5 Homolog 2; Protein Unc-5 Homolog B; p53-regulated Receptor for Death and Life Protein 1
Concentration:
1mg/ml after reconstitution.
EClass:
32160000
Endotoxin:
<0.1EU/µg purified protein (LAL test; Lonza).
Form (Short):
liquid
Formulation:
Lyophilized. Contains PBS.
Handling Advice:
After reconstitution, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.Centrifuge lyophilized vial before opening and reconstitution.PBS containing at least 0.1% BSA should be used for further dilutions.
Long Description:
Protein. The extracellular region of human UNC5B (aa 28-363) is fused at the C-terminus to the Fc portion of human IgG1. Source: HEK 293 cells. Endotoxin content: <0.1EU/µg purified protein (LAL test; Lonza). Lyophilized. Contains PBS. Binds to mouse and human Netrin-1. Purity: >95% (SDS-PAGE). UNC5B is a receptor for the netrin family of guidance molecules. It was identified as a mediator of the repulsive response in neurons and it is the only known netrin receptor with prominent endothelial expression. It has an important role in angiogenesis signaling.
Molecular Weight:
~80kDa (SDS-PAGE).
NCBI, Uniprot Number:
Q8IZJ1
Package Type:
Plastic Vial
Product Description:
UNC5B is a receptor for the netrin family of guidance molecules. It was identified as a mediator of the repulsive response in neurons and it is the only known netrin receptor with prominent endothelial expression. It has an important role in angiogenesis signaling.
Purity:
>95% (SDS-PAGE)
Sequence:
The extracellular region of human UNC5B (aa 28-363) is fused at the C-terminus to the Fc portion of human IgG1.
Source / Host:
HEK 293 cells
Specificity:
Binds to mouse and human Netrin-1.
TAGs:
Fc
Transportation:
Non-hazardous
UNSPSC Category:
Other Proteins
UNSPSC Number:
12352202
Use & Stability:
Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.