Chemodex

6-CFDA

Product Code:
CDX-C0040
Supplier:
Chemodex
Regulatory Status:
RUO
Shipping:
Ambient
Storage:
Short term: +4°C. Long term: +4°C
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Chemical Structure
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Chemical Structure

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This product comes from: Switzerland.
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Further Information

Alternate Names/Synonyms:
6-Carboxyfluorescein diacetate
Appearance:
White to yellow powder.
CAS:
06/03/3348
EClass:
32160000
Form (Short):
liquid
Handling Advice:
Protect from light and moisture.
InChi:
InChI=1S/C25H16O9/c1-12(26)31-15-4-7-18-21(10-15)33-22-11-16(32-13(2)27)5-8-19(22)25(18)20-9-14(23(28)29)3-6-17(20)24(30)34-25/h3-11H,1-2H3,(H,28,29)
InChiKey:
QMOGCCYGOPYYNT-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 3348-03-6. Formula: C25H16O9. MW: 460.39. Synthetic. Used to differentiate viable cells from apoptotic cells. Live cells that are not apoptotic accumulate 6-carboxyfluorescein but do not accumulate annexin. CFDA enter cells and are hydrolysed more slowly than FDA. CFDA and FDA hydrolyses obey Michaelis-Menten kinetics with Km values of around 19 and 2 microM, respectively.
MDL:
MFCD00036871
Molecular Formula:
C25H16O9
Molecular Weight:
460.39
Package Type:
Vial
Product Description:
Used to differentiate viable cells from apoptotic cells. Live cells that are not apoptotic accumulate 6-carboxyfluorescein but do not accumulate annexin. CFDA enter cells and are hydrolysed more slowly than FDA. CFDA and FDA hydrolyses obey Michaelis-Menten kinetics with Km values of around 19 and 2 microM, respectively.
Purity:
>95% (HPLC)
SMILES:
CC(=O)OC1=CC2=C(C=C1)C1(OC(=O)C3=C1C=C(C=C3)C(O)=O)C1=CC=C(OC(C)=O)C=C1O2
Solubility Chemicals:
Soluble in DMSO.
Source / Host:
Synthetic.
Transportation:
Non-hazardous
UNSPSC Category:
Fluorescent Reagents
UNSPSC Number:
41105331
Use & Stability:
Stable for at least 2 years after receipt when stored at +4°C.

References

(1) C. Dive et al.; Mol. Cell. Probes 2, 131 (1998) | (2) N. Yamaguchi et al.; J. Appl. Microbiol. 83, 43 (1997) | (3) P.J. Oefner et al.; Anal. Biochem. 223, 39 (1994)