Chemodex

7-Diethylaminocoumarin-3-carboxylic acid N-succinimidyl ester

Product Code:
 
CDX-D0037
Product Group:
 
Dyes, Stains, and Probes
Supplier:
 
Chemodex
Regulatory Status:
 
RUO
Shipping:
 
Ambient
Storage:
 
Short term: +4°C. Long term: -20°C
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Chemical Structure
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Chemical Structure

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CDX-D0037-M100100 mg£202.00
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CDX-D0037-G0011 g£1,581.00
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Further Information

Alternate Names/Synonyms:
7-DCCAE
Appearance:
Yellow solid.
CAS:
139346-57-9
EClass:
32160000
Form (Short):
liquid
Handling Advice:
Protect from light and moisture.
InChi:
InChI=1S/C18H18N2O6/c1-3-19(4-2)12-6-5-11-9-13(17(23)25-14(11)10-12)18(24)26-20-15(21)7-8-16(20)22/h5-6,9-10H,3-4,7-8H2,1-2H3
InChiKey:
NUNPVRICKDZFLK-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 139346-57-9. Formula: C18H18N2O6. MW: 358.35. Synthetic. Derivatives of 7-aminocoumarins are the most extensively utilized labeling reagents for preparing brightly blue fluorescent conjugates of proteins and nucleic acid. Labeled amino acids are detected with visible semiconductor laser fluorometry using second harmonic emission (415 nm) of the near-infrared semiconductor laser. Arginine, proline, serine and glycine have been detected with detection limits around 100 amol levels. The fluorescent-labelling better matches the excitation-wavelength of standard blue lasers than conventional fluorescein-isothiocyyanate.
MDL:
MFCD00467585
Molecular Formula:
C18H18N2O6
Molecular Weight:
358.35
Package Type:
Vial
Product Description:
Derivatives of 7-aminocoumarins are the most extensively utilized labeling reagents for preparing brightly blue fluorescent conjugates of proteins and nucleic acid. Labeled amino acids are detected with visible semiconductor laser fluorometry using second harmonic emission (415 nm) of the near-infrared semiconductor laser. Arginine, proline, serine and glycine have been detected with detection limits around 100 amol levels. The fluorescent-labelling better matches the excitation-wavelength of standard blue lasers than conventional fluorescein-isothiocyyanate.
Purity:
>96% (HPLC)
SMILES:
CCN(CC)C1=CC2=C(C=C1)C=C(C(=O)ON1C(=O)CCC1=O)C(=O)O2
Solubility Chemicals:
Soluble in DMSO, DMF or acetonitrile.
Source / Host:
Synthetic.
Transportation:
Non-hazardous
UNSPSC Category:
Fluorescent Reagents
UNSPSC Number:
41105331
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.

References

(1) B. Steinberg et al.; PNAS 104(22), 9523 (2007) | (2) A.K. Bhunia et al.; Chem. Biol. Chem. 8(14), 1642 (2007) | (3) T. Higashijima et al.; Anal. Chem. 64, 711 (1992)