Moxifloxacin hydrochloride
Product Code:
CDX-M0189
CDX-M0189
Regulatory Status:
RUO
RUO
Shipping:
Ambient
Ambient
Storage:
Short term: +4°C. Long term: -20°C
Short term: +4°C. Long term: -20°C
No additional charges, what you see is what you pay! *
| Code | Size | Price |
|---|
| CDX-M0189-M050 | 50 mg | £90.00 |
Quantity:
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This product comes from: Switzerland.
Typical lead time: 7-10 working days.
Contact us for more accurate information.
Typical lead time: 7-10 working days.
Contact us for more accurate information.
- Further Information
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Further Information
Alternate Names/Synonyms:
BAY 12-8039; Alelox; 1-Cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydropyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride
Appearance:
Light yellow powder.
CAS:
186826-86-8
EClass:
32160000
Form (Short):
solid
Handling Advice:
Protect from light and moisture.
InChi:
InChI=1S/C21H24FN3O4.ClH/c1-29-20-17-13(19(26)14(21(27)28)9-25(17)12-4-5-12)7-15(22)18(20)24-8-11-3-2-6-23-16(11)10-24;/h7,9,11-12,16,23H,2-6,8,10H2,1H3,(H,27,28);1H/t11-,16+;/m0./s1
InChiKey:
IDIIJJHBXUESQI-DFIJPDEKSA-N
Long Description:
Chemical. CAS: 186826-86-8. Formula: C21H24FN3O4 . HCl. MW: 401.43 . 36.46. Moxifloxacin is a fourth-generation synthetic broad-spectrum fluoroquinolone antibiotic. It is used against both Gram-positive and Gram-negative bacteria and to treat bacterial infections associated with bronchitis, sinusitis, and other conditions. Fluoroquinolones stabilize DNA strand breaks created by DNA gyrase (Topo II) and topoisomerase IV by binding to the enzyme-DNA complex. Compared to mammalian DNA gyrase, moxifloxacin has 100 times higher affinity for bacterial DNA gyrase. Can also be used as reference compound.
MDL:
MFCD00949117
Molecular Formula:
C21H24FN3O4 . HCl
Molecular Weight:
401.43 . 36.46
Package Type:
Vial
Product Description:
Moxifloxacin is a fourth-generation synthetic broad-spectrum fluoroquinolone antibiotic. It is used against both Gram-positive and Gram-negative bacteria and to treat bacterial infections associated with bronchitis, sinusitis, and other conditions. Fluoroquinolones stabilize DNA strand breaks created by DNA gyrase (Topo II) and topoisomerase IV by binding to the enzyme-DNA complex. Compared to mammalian DNA gyrase, moxifloxacin has 100 times higher affinity for bacterial DNA gyrase. Can also be used as reference compound.
Purity:
>97% (NMR)
SMILES:
O=C1C(C(O)=O)=CN(C2CC2)C3=C(OC)C([NH+]4C[C@](NCCC5)([H])[C@]5([H])C4)=C(F)C=C31.[Cl-]
Solubility Chemicals:
Soluble in DMSO (10mg/ml) or water (5mg/ml).
Source / Host:
Synthetic
Transportation:
Non-hazardous
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
Documents
References
(1) M. Souli, et al.; Int. J. Antimicrob. Agents. 10, 23 (1998) | (2) C. Ballow, et al.; Clin. Ther. 21, 513 (1999) | (3) A. Dalhoff, et al.; Clin. Infect. Dis. 32, S22 (2001) | (4) R. Kishii, et al.; Antimicrob. Agents Chemother. 47, 77 (2003) | (5) M. Miravitlles; J. Chron. Obstruct. Pulmon. Dis. 2, 191 (2007) | (6) M. Miravitlles & A. Anzueto; Expert Opin. Pharmacother. 9, 1755 (2008) (Review) | (7) H. Takiff & E. Guerrero; Antimicrob. Agents Chemother. 55, 5421 (2011) | (8) M.M. Al Omari, et al.; Profiles Drug Subst. Excip. Relat. Methodol. 39, 299 (2014) (Review)