3Helix

Collagen Hybridizing Peptide, Biotin Conjugate (B-CHP)

Product Code:
 
3H-BIO300
Product Group:
 
Peptides
Supplier:
 
3Helix
Regulatory Status:
 
RUO
Applications:
  • Immunocytochemistry (ICC)
  • Immunofluorescence (IF)
Shipping:
 
Ambient
Storage:
 
-20°C as powder, 4 °C after reconstitution in water
1 / 2
2 / 2

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3H-BIO300300 ug£597.00
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This product comes from: United States.
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  • Further Information
  • Documents
  • References
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Further Information

Conjugate:
Single biotin tag per peptide
Molecular Mass(KD):
2762.01 g/mol
Product information:
The collagen hybridizing peptide (CHP) is a novel and unique peptide that specifically binds unfolded collagen chains, both?in vitro?and?in vivo.[1,2,3]?By sharing the Gly-X-Y repeating sequence of natural collagen, CHP has a strong capability to hybridize with denatured collagen chains by reforming the triple helical structure, in a fashion similar to DNA fragments annealing to complementary DNA strands. CHP is extremely specific: it has negligible affinity to intact collagen molecules due to lack of binding sites, and it is inert towards non-specific binding because of its neutral and hydrophilic nature.
Purity:
95%

References

  • Int J Mol Sci. 2022 Apr 12;23(8):4245. doi: 10.3390/ijms23084245.Read more here.
  • Feng, Xiaotian et al. ?Apical expansion of calvarial osteoblasts and suture patency is dependent on graded fibronectin cues.??bioRxiv : the preprint server for biology?2023.01.16.524278. 16 Jan. 2023, doi:10.1101/2023.01.16.524278. Preprint.Read more here.
  • Aging Cancer. 2022 Jun;3(2):116-129. doi: 10.1002/aac2.12049. Epub 2022 Apr 19.Read more here.
  • Jin, Hyo-Eon et al. ?Collagen mimetic peptide engineered M13 bacteriophage for collagen targeting and imaging in cancer.??Biomaterials?vol. 35,33 (2014): 9236-45. doi:10.1016/j.biomaterials.2014.07.044Read more here.
  • Vagnozzi, Ronald J et al. ?An acute immune response underlies the benefit of cardiac stem?cell therapy.??Nature?vol. 577,7790 (2020): 405-409. doi:10.1038/s41586-019-1802-2Read more here.
  • Wang, William Y et al. ?Dynamic Endothelial Stalk Cell-Matrix Interactions Regulate Angiogenic Sprout Diameter.??Frontiers in bioengineering and biotechnology?vol. 9 620128. 19 Mar. 2021, doi:10.3389/fbioe.2021.620128Read more here.
  • Lee, Soo Jung et al. ?A midposition NOTCH3 truncation in inherited cerebral small vessel disease may affect the protein interactome.??The Journal of biological chemistry?vol. 299,1 (2023): 102772. doi:10.1016/j.jbc.2022.102772Read more here.
  • Filiberti, Adrian et al. ?An intact complement system dampens cornea inflammation during acute primary HSV-1 infection.??Scientific reports?vol. 11,1 10247. 13 May. 2021, doi:10.1038/s41598-021-89818-9Read more here.
  • Filiberti, Adrian et al. ?Loss of Osteopontin Expression Reduces HSV-1-Induced Corneal Opacity.??Investigative ophthalmology & visual science?vol. 61,10 (2020): 24. doi:10.1167/iovs.61.10.24Read more here.
  • Viiklepp, Kristina et al. ?C1r Upregulates Production of Matrix Metalloproteinase-13 and Promotes Invasion of Cutaneous Squamous Cell Carcinoma.??The Journal of investigative dermatology?vol. 142,5 (2022): 1478-1488.e9. doi:10.1016/j.jid.2021.10.008Read more here.
  • Zhang, Xiaojie et al. ?Hydrolysis of a second Asp-Pro site at the N-terminus of NOTCH3 in inherited vascular dementia.??Scientific reports?vol. 11,1 17246. 26 Aug. 2021, doi:10.1038/s41598-021-96679-9Read more here.
  • Polymers (Basel). 2023 Sep 7;15(18):3683. doi: 10.3390/polym15183683.Read more here.
  • Rognoni, Emanuel et al. ?Role of distinct fibroblast lineages and immune cells in dermal repair following UV radiation-induced tissue damage.??eLife?vol. 10 e71052. 23 Dec. 2021, doi:10.7554/eLife.71052Read more here.
  • J Histochem Cytochem. 2024 Feb;72(2):79-94. doi: 10.1369/00221554231225995. Epub 2024 Jan 24.Read more here.
  • Hettinger, Zachary R et al. ?Mechanotherapy Reprograms Aged Muscle Stromal Cells to Remodel the Extracellular Matrix during Recovery from Disuse.??Function (Oxford, England)?vol. 3,3 zqac015. 24 Mar. 2022, doi:10.1093/function/zqac015Read more here.