Collagen Hybridizing Peptide, Cy3 Conjugate (R-CHP)
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| Code | Size | Price |
|---|
| 3H-RED300 | 300 ug | £597.00 |
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This product comes from: United States.
Typical lead time: 14-21 working days.
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Typical lead time: 14-21 working days.
Contact us for more accurate information.
- Further Information
- Documents
- References
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Further Information
Conjugate:
Single sulfo-Cyanine3 tag per peptide
Molecular Mass(KD):
3191.44 g/mol
Product information:
The collagen hybridizing peptide (CHP) is a novel and unique peptide that specifically binds unfolded collagen chains, both?in vitro?and?in vivo.[1,2,3]?By sharing the Gly-X-Y repeating sequence of natural collagen, CHP has a strong capability to hybridize with denatured collagen chains by reforming the triple helical structure, in a fashion similar to DNA fragments annealing to complementary DNA strands. CHP is extremely specific: it has negligible affinity to intact collagen molecules due to lack of binding sites, and it is inert towards non-specific binding because of its neutral and hydrophilic nature.
Purity:
90%
Documents
References
- https://doi.org/10.1038/s44341-024-00006-y
- J Am Chem Soc. 2023 May 24;145(20):10901-10916. doi: 10.1021/jacs.3c00713. Epub 2023 May 9.Read more here.
- Khajuria, Deepak Kumar et al. ?Aberrant structure of fibrillar collagen and elevated levels of advanced glycation end products typify delayed fracture healing in the diet-induced obesity mouse model.??Bone?vol. 137 (2020): 115436. doi:10.1016/j.bone.2020.115436Read more here.
- J Cardiovasc Transl Res. 2023 Apr;16(2):463-472. doi: 10.1007/s12265-022-10316-y. Epub 2022 Sep 12.Read more here.
- Georgieva, Veronika S et al. ?Ablation of the miRNA cluster 24 in cartilage and osteoblasts impairs bone remodeling.??Scientific reports?vol. 12,1 9116. 1 Jun. 2022, doi:10.1038/s41598-022-13231-zRead more here.
- Flinn, Michael A et al. ?Myofibroblast Ccn3 is regulated by Yap and Wwtr1 and contributes to adverse cardiac outcomes.??Frontiers in cardiovascular medicine?vol. 10 1142612. 14 Mar. 2023, doi:10.3389/fcvm.2023.1142612Read more here.
- Lambert, Karen et al. ?Grape polyphenols and exercise training have distinct molecular effects on cardiac hypertrophy in a model of obese insulin-resistant rats.??The Journal of nutritional biochemistry?vol. 87 (2021): 108522. doi:10.1016/j.jnutbio.2020.108522Read more here.
- Chen, Bob et al. ?Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps.??Cell?vol. 184,26 (2021): 6262-6280.e26. doi:10.1016/j.cell.2021.11.031Read more here.
- Gutman, Hila et al. ?Matrix Metalloproteinases Expression Is Associated with SARS-CoV-2-Induced Lung Pathology and Extracellular-Matrix Remodeling in K18-hACE2 Mice.??Viruses?vol. 14,8 1627. 26 Jul. 2022, doi:10.3390/v14081627Read more here.
- JOR Spine. 2024 Jul 31;7(3):e1359. doi: 10.1002/jsp2.1359. eCollection 2024 Sep.Read more here.
- Kober, Katharina Isabelle et al. ?Loxl2 is dispensable for dermal development, homeostasis and tumour stroma formation.??PloS one?vol. 13,6 e0199679. 28 Jun. 2018, doi:10.1371/journal.pone.0199679Read more here.
- Dev Biol. 2021 Sep;477:155-163. doi: 10.1016/j.ydbio.2021.05.016. Epub 2021 May 28.Read more here.
- Ho, Yen-Chun et al. ?PROX1 Inhibits PDGF-B Expression to Prevent Myxomatous Degeneration of Heart Valves.??Circulation research?vol. 133,6 (2023): 463-480. doi:10.1161/CIRCRESAHA.123.323027Read more here.
- Rappold, Ronja, et al. "Salmonella?driven intestinal edema in mice is characterized by tensed fibronectin fibers."?The FEBS Journal?(2024).Read more here.
- Front Pharmacol. 2021 Jul 28;12:669037. doi: 10.3389/fphar.2021.669037. eCollection 2021.Read more here.