Further Information
GZMB, CCPI, CGL-1, Cathepsin G-like 1, CSP-B, CTLA-1, CTLA1, CGL1, CSPB, Fragmentin 2, GRB, HLP, Human lymphocyte protein, Fragmentin-2, SECT, Lymphocyte protease, T-cell serine protease 1-3E, C11, CTSGL1, Cytotoxic serine protease B, Granzyme B, Granzyme-2
WB: 1:500 - 1:2000
IF: 1:50 - 1:200
Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Recombinant fusion protein containing a sequence corresponding to amino acids 148-247 of human GZMB (NP_004122.2).
3002
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
GZMB
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 27kDa
Affinity purification
Apoptosis, Cell Cycle, Immunology, Innate Immunity
P10144
Optimal dilutions for each application to be determined by the researcher.
