TargetMol

CEP-28122 mesylate salt (1022958-60-6 free base)

Product Code:
 
TAR-T10759
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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This product comes from: Austria.
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Further Information

Bioactivity:
CEP-28122 mesylate salt is a highly selective orally active ALK inhibitor (IC50: 1.9 nM in an enzyme-based TRF assay).
CAS:
T10759
Formula:
C29H39ClN6O6S
Molecular Weight:
635.17
Pathway:
Tyrosine Kinase/Adaptors; Angiogenesis
Purity:
0.9919
SMILES:
COC1=C(C=CC2=C1CC[C@H](CC2)N3CCOCC3)NC4=NC=C(C(N[C@@H]5[C@@H]6C[C@H]([C@@H]5C(N)=O)C=C6)=N4)Cl.CS(=O)(O)=O
Target:
ALK

Documents

References

1. Cheng M, et al. CEP-28122, a highly potent and selective orally active inhibitor of anaplastic lymphoma kinase with antitumor activity in experimental models of human cancers. Mol Cancer Ther. 2012 Mar;11(3):670-679.