Irisin (rec.) (HEK293)
Product Code:
AG-40B-0102
AG-40B-0102
Host Type:
HEK 293 cells
HEK 293 cells
Regulatory Status:
RUO
RUO
Target Species:
- Human
- Mouse
Shipping:
Blue Ice
Blue Ice
Storage:
Short term: +4°C. Long term: -20°C
Short term: +4°C. Long term: -20°C
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This product comes from: Switzerland.
Typical lead time: 7-10 working days.
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Typical lead time: 7-10 working days.
Contact us for more accurate information.
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Further Information
Alternate Names/Synonyms:
Fibronectin Type III Domain-containing Protein 5 (cleaved); Fibronectin Type III Repeat-containing Protein 2 (cleaved); FNDC5 (cleaved)
Concentration:
0.1mg/ml after reconstitution.
EClass:
32160000
Endotoxin:
<0.1EU/ug purified protein (LAL test; Lonza).
Form (Short):
solid
Formulation:
Lyophilized. Contains PBS.
Handling Advice:
After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. PBS containing at least 0. 1% BSA should be used for further dilutions.
Long Description:
Recombinant protein. Irisin (human, aa 32-143 /mouse, aa 29-140) is FLAG ®-tagged at the N-terminus. Irisin has 100% identity between mouse, rat, monkey and human. Source: HEK 293 cells. Lyophilized. Contains PBS. Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone Irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure.
Molecular Weight:
~26kDa
NCBI, Uniprot Number:
Q8NAU1
Product Description:
Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone Irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure.
Purity:
>95% (SDS-PAGE)
Sequence:
Irisin (human, aa 32-143 /mouse, aa 29-140) is FLAG ®-tagged at the N-terminus. Irisin has 100% identity between mouse, rat, monkey and human.
Source / Host:
HEK 293 cells
TAGs:
FLAG
Transportation:
Non-hazardous
UNSPSC Number:
12352202
Use & Stability:
Stable for at least 6 months after receipt when stored at -20°C.