Leinco Technologies

Anti-Human CD14 - Biotin

Product Code:
LEI-C154
Product Group:
Primary Antibodies
Host Type:
Mouse
Antibody Isotype:
IgG2a
Antibody Clonality:
Monoclonal
Antibody Clone:
UCHM-1
Regulatory Status:
RUO
Target Species:
Human
Application:
Flow Cytometry
Product Type:
Tagged
Shipping:
Ambient
Storage:
This biotinylated antibody is stable when stored at 2-8°C. Do not freeze.
 

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This product comes from: United States.
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Further Information

Antigen Distribution:
CD14 is expressed on monocytes, macrophages, dendritic cells, and granulocytes.
Concentration:
0.5 mg/ml
Conjugate/Tag/Label:
Biotin
Format:
This biotinylated antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Formulation:
This biotinylated antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Long Description:
CD14 is a 53-55 kD GPI-anchored single chain glycoprotein that plays a role in the clearance of gram-negative pathogens by interacting with other proteins, including TLR-4 and MD-2, to mediate the innate immune response to bacterial lipopolysaccharide (LPS). As a high-affinity receptor for LPS, it is involved in the upregulation of adhesion molecules and cytokine expression in monocytes and neutrophils.
NCBI Gene:
929
Target:
CD14

References

1. Freyssinet, JM et al. (1997) J Clin Invest. 99(7): 1546?1554. PubMed 2. Ulrich, Costabel et al. (1995) CHEST 108: 1614 3. Ulevitch, RJ et al. (1993) Immunobiology 187: 227 4. Schumann, RR et al. (1994) Medical Microbiol Immunol. 183: 279 5. Verhasselt, V et al. (1997) J Immunol. 158: 2919 6. Kirkland, TN et al. (2000) J Biol Chem. 275: 3144