TargetMol

HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Tetramer Protein, Human, MHC (His & Avi)

Product Code:
TAR-TMPK-01544
Product Group:
MHC Tetramers
Supplier:
TargetMol
Regulatory Status:
RUO
Shipping:
cool pack
Storage:
-20°C
1 / 1
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This product comes from: Austria.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with β2-microglobulin, and is able to present peptides to cytotoxic lymphocytes. The main function of HLA-E under normal conditions is to present peptides derived from the leader sequences of classical HLA class I proteins, thus serving for monitoring of expression of these molecules performed by cytotoxic lymphocytes.
Purity:
98%

References

1.Kanevskiy L, et al. Dimorphism of HLA-E and its Disease Association. Int J Mol Sci. 2019 Nov 4;20(21):5496. doi: 10.3390/ijms20215496. PMID: 31690066; PMCID: PMC6862560.