Amphotericin B Solution (250 ug/mL), Sterile

Amphotericin B solution is a broad-spectrum polyene antifungal antibiotic which is unstable at room temperature and susceptible to degradation by light, heat, and acid. The solution exerts its strongest antifungal activity at pH 6.0 to 7.5. Amphotericin B binds to ergosterol on the fungal cell membrane, which will damage membrane, increase permeability, leak intracellular substances and disrupt normal metabolism. As bacterial cell membranes do not contain ergosterol, amphotericin B is ineffective against bacteria. TargetMol's amphotericin B solution is a sterile, filtered and ready-to-use solution for cell culture, containing 250 ug/mL of amphotericin B. It is recommended for use in cell culture application at 0.25-2.5 ug/mL of amphotericin B. Dilute the solution as experimental needs.