KactusBio Inc.

Chimeric HLA-A*02:01 (ma3) &mB2M&TERT (ILAKFLHWL) Monomer Protein (MHC-HM107)

Product Code:
 
KAC-MHC-HM107
Product Group:
 
MHC Monomers
Supplier:
 
KactusBio Inc.
Regulatory Status:
 
RUO
Target Species:
 
Human
Shipping:
 
Shipped with dry ice.
Storage:
 
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Chimeric HLA-A*02:01 (mα3) &mB2M&TERT (ILAKFLHWL) Monomer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%
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The purity of Chimeric HLA-A*02:01 (mα3) &mB2M&TERT (ILAKFLHWL) Monomer is greater than 95% as determined by SEC-HPLC.
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Chimeric HLA-A*02:01 (mα3) &mB2M&TERT (ILAKFLHWL) Monomer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%
The purity of Chimeric HLA-A*02:01 (mα3) &mB2M&TERT (ILAKFLHWL) Monomer is greater than 95% as determined by SEC-HPLC.

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CodeSizePrice
KAC-MHC-HM107-100UG100UG£414.00
Quantity:
KAC-MHC-HM107-500UG500UG£1,061.00
Quantity:
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This product comes from: United States.
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Further Information

Background:
The human telomerase catalytic subunit human telomerase reverse transcriptase (hTERT) is expressed in many human cancer cells derived from multiple tissues, but infrequently in normal cells. Thus, hTERT is an attractive candidate target for tumor immunotherapy. hTERT:540?548 peptide (p540, ILAKFLHWL) has been identified as an effective HLA-A*0201-restricted T-cell epitope, an effective T-cell-based cancer treatment, including vaccines, against hTERT will likely require the identification of other MHC class I-restricted epitopes in this antigen.
Biotinylated:
no
Description:
Recombinant Chimeric HLA-A*02:01 (mα3) &mB2M&TERT (ILAKFLHWL) Monomer Protein is expressed from HEK293 with His tag at the C-terminus.It contains Gly25-Thr206 (Human HLA-A*02:01 α1&α2) and Asp207-Glu299 (Mouse H-2Ld α3), Ile21-Met119 (mB2M) and ILAKFLHWL peptide.
Endotoxin:
Less than 1EU per ug by the LAL method.
Exact Sequence:
Gly25-Thr206(Human HLA-A*02:01 α1&α2) & Asp207-Glu299(Mouse H-2Ld α3), Ile21-Met119(mB2M) and ILAKFLHWL peptide
Expression System:
HEK293
Form:
Liquid
Formulation:
Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Gene/Protein ID:
A0A140T913(Human HLA-A*02:01 α1&α2)&P01897(Mouse H-2Ld α3)&&P01887(Mouse B2M)&ILAKFLHWL
Molecular Weight:
The protein has a predicted MW of 48.00 kDa. Due to glycosylation, the protein migrates to 50-65 kDa based on Bis-Tris PAGE result.
Purity:
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Tag:
C-His
Target:
HLA-A*02:01 (mα3) &mB2M&TERT (ILAKFLHWL) Monomer

Documents