KactusBio Inc.

Chimeric HLA-A*02:01 (ma3) &mB2M&MAGE-A3 (KVAELVHFL) Monomer Protein (MHC-HM105)

Product Code:
 
KAC-MHC-HM105
Product Group:
 
MHC Monomers
Supplier:
 
KactusBio Inc.
Regulatory Status:
 
RUO
Shipping:
 
Shipped with dry ice.
Storage:
 
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Chimeric HLA-A*02:01 (mα3) &mB2M&MAGE-A3 (KVAELVHFL) Monomer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%
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The purity of Chimeric HLA-A*02:01 (mα3) &mB2M&MAGE-A3 (KVAELVHFL) Monomer is greater than 95% as determined by SEC-HPLC.
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Chimeric HLA-A*02:01 (mα3) &mB2M&MAGE-A3 (KVAELVHFL) Monomer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%
The purity of Chimeric HLA-A*02:01 (mα3) &mB2M&MAGE-A3 (KVAELVHFL) Monomer is greater than 95% as determined by SEC-HPLC.

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CodeSizePrice
KAC-MHC-HM105-100UG100UG£414.00
Quantity:
KAC-MHC-HM105-500UG500UG£1,061.00
Quantity:
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This product comes from: United States.
Typical lead time: 14-21 working days.
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Further Information

Background:
Melanoma antigen family A, 3 (MAGE-A3) is a cancer-testis antigen whose expression has been demonstrated in a wide array of malignancies including melanoma, brain, breast, lung and ovarian cancer. In addition, its ability to elicit spontaneous humoral and cellular immune responses has been shown in cancer patients.
Biotinylated:
no
Description:
Recombinant Chimeric HLA-A*02:01 (mα3) &mB2M&MAGE-A3 (KVAELVHFL) Monomer Protein is expressed from HEK293 with His tag at the C-terminus.It contains Gly25-Thr206 (Human HLA-A*02:01 α1&α2) and Asp207-Glu299 (Mouse H-2Ld α3), Ile21-Met119 (mB2M) and KVAELVHFL peptide.
Endotoxin:
Less than 1EU per ug by the LAL method.
Exact Sequence:
Gly25-Thr206(Human HLA-A*02:01 α1&α2) & Asp207-Glu299(Mouse H-2Ld α3), Ile21-Met119(mB2M) and KVAELVHFL peptide
Expression System:
HEK293
Form:
Liquid
Formulation:
Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Gene/Protein ID:
A0A140T913(Human HLA-A*02:01 α1&α2)&P01897(Mouse H-2Ld α3)&&P01887(Mouse B2M)&KVAELVHFL
Molecular Weight:
The protein has a predicted MW of 48.00 kDa. Due to glycosylation, the protein migrates to 50-65 kDa based on Bis-Tris PAGE result.
Purity:
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Tag:
C-His
Target:
HLA-A*02:01 (mα3) &mB2M&MAGE-A3 (KVAELVHFL) Monomer

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