KactusBio Inc.

Human HLA-A*03:01&B2M&gp100 (ALLAVGATK) Tetramer Protein (MHC-HM463T)

Product Code:
 
KAC-MHC-HM463T
Product Group:
 
MHC Tetramers
Supplier:
 
KactusBio Inc.
Host Type:
 
HEK 293 cells
Regulatory Status:
 
RUO
Target Species:
 
Human
Shipping:
 
Shipped at ambient temperature.
Storage:
 
-20 to -80°C for 12 months as supplied from date of receipt.-80°C for 3 months after reconstitution.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Human HLA-A*03:01&B2M&gp100 (ALLAVGATK) Tetramer on Bis-Tris PAGE under Non reducing (N) condition. The purity is greater than 95%
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The purity of Human HLA-A*03:01&B2M&gp100 (ALLAVGATK) Tetramer is greater than 95% as determined by SEC-HPLC.
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Human HLA-A*03:01&B2M&gp100 (ALLAVGATK) Tetramer on Bis-Tris PAGE under Non reducing (N) condition. The purity is greater than 95%
The purity of Human HLA-A*03:01&B2M&gp100 (ALLAVGATK) Tetramer is greater than 95% as determined by SEC-HPLC.

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CodeSizePrice
KAC-MHC-HM463T-100UG100UG£676.00
Quantity:
KAC-MHC-HM463T-500UG500UG£2,463.00
Quantity:
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Further Information

Background:
Immunization against the ALLAVGATK peptide may occur in melanoma patients and that the immunogenicity of this peptide is similar to that of the majority of melanoma differentiation antigens defined to date. Therefore, the use of ALLAVGATK in active immunotherapy for HLA-A3 melanoma patients, for whom no other immunogenic peptide has been so far described, remains a distinct possibility, providing that patients treated in vivo with this peptide develop a better in vitro response than already demonstrated for HLA-A2 epitopes generated from this same antigenic protein.
Biotinylated:
no
Description:
Recombinant Human HLA-A*03:01&B2M&gp100 (ALLAVGATK) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus, tetramer is assembled by biotinylated monomer and streptavidin.It contains Gly25-Thr305 (HLA-A*03:01), Ile21-Met119 (B2M) and ALLAVGATK peptide.
Endotoxin:
Less than 1EU per ug by the LAL method.
Exact Sequence:
Gly25-Thr305(HLA-A*03:01), Ile21-Met119(B2M) and ALLAVGATK peptide
Expression System:
HEK293
Form:
Lyophilized
Formulation:
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Gene/Protein ID:
NP_002107.3(HLA-A*03:01)&P61769(B2M)&ALLAVGATK
Molecular Weight:
The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reducing (N) condition based on Bis-Tris PAGE result.
Purity:
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Reconstitution:
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Tag:
C-His-Avi
Target:
HLA-A*03:01&B2M&gp100 (ALLAVGATK) Tetramer

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