KactusBio Inc.

Biotinylated Human HLA-A*02:01&B2M&MAGE-A3 (KVAELVHFL) Monomer Protein (MHC-HM461B)

Product Code:
 
KAC-MHC-HM461B
Product Group:
 
MHC Monomers
Supplier:
 
KactusBio Inc.
Regulatory Status:
 
RUO
Target Species:
 
Human
Shipping:
 
Shipped at ambient temperature.
Storage:
 
-20 to -80°C for 12 months as supplied from date of receipt. -80°C for 3 months after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Biotinylated Human HLA-A*02:01&B2M&MAGE-A3 (KVAELVHFL) Monomer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%
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The purity of Biotinylated Human HLA-A*02:01&B2M&MAGE-A3 (KVAELVHFL) Monomer is greater than 95% as determined by SEC-HPLC.
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Biotinylated Human HLA-A*02:01&B2M&MAGE-A3 (KVAELVHFL) Monomer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%
The purity of Biotinylated Human HLA-A*02:01&B2M&MAGE-A3 (KVAELVHFL) Monomer is greater than 95% as determined by SEC-HPLC.

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CodeSizePrice
KAC-MHC-HM461B-100UG100UG£327.00
Quantity:
KAC-MHC-HM461B-500UG500UG£1,073.00
Quantity:
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This product comes from: United States.
Typical lead time: 14-21 working days.
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Further Information

Background:
Melanoma antigen family A, 3 (MAGE-A3) is a cancer-testis antigen whose expression has been demonstrated in a wide array of malignancies including melanoma, brain, breast, lung and ovarian cancer. In addition, its ability to elicit spontaneous humoral and cellular immune responses has been shown in cancer patients.
Biotinylated:
yes
Description:
Recombinant Biotinylated Human HLA-A*02:01&B2M&MAGE-A3 (KVAELVHFL) Monomer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gly25-Thr305 (HLA-A*02:01), Ile21-Met119 (B2M) and KVAELVHFL peptide.
Endotoxin:
Less than 1EU per ug by the LAL method.
Exact Sequence:
Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and KVAELVHFL peptide
Expression System:
HEK293
Form:
Lyophilized
Formulation:
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Gene/Protein ID:
A0A140T913(HLA-A*02:01)&P61769(B2M)&KVAELVHFL
Molecular Weight:
The protein has a predicted MW of 50.50 kDa. Due to glycosylation, the protein migrates to 50-65 kDa based on Bis-Tris PAGE result.
Purity:
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Reconstitution:
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Tag:
C-His-Avi
Target:
HLA-A*02:01&B2M&MAGE-A3 (KVAELVHFL) Monomer

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