KactusBio Inc.

Human HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Tetramer Protein (MHC-HM459T)

Product Code:
 
KAC-MHC-HM459T
Product Group:
 
MHC Tetramers
Supplier:
 
KactusBio Inc.
Host Type:
 
HEK 293 cells
Regulatory Status:
 
RUO
Target Species:
 
Human
Shipping:
 
Shipped at ambient temperature.
Storage:
 
-20 to -80°C for 12 months as supplied from date of receipt. -80°C for 3 months after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Human HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Tetramer on Bis-Tris PAGE under Non reducing (N) condition. The purity is greater than 95%
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The purity of Human HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Tetramer is greater than 95% as determined by SEC-HPLC.
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Human HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Tetramer on Bis-Tris PAGE under Non reducing (N) condition. The purity is greater than 95%
The purity of Human HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Tetramer is greater than 95% as determined by SEC-HPLC.

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CodeSizePrice
KAC-MHC-HM459T-100UG100UG£676.00
Quantity:
KAC-MHC-HM459T-500UG500UG£2,463.00
Quantity:
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This product comes from: United States.
Typical lead time: 14-21 working days.
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Further Information

Background:
MAGE-A10 is a subtype of the Melanoma-associated antigen A (MAGE-A), a class of tumor antigens that are extensively expressed in various histological types of tumors and represents an attractive target for tumor immunotherapy. High-level expression of MAGE-A10 improved the anti-tumor immune cytotoxicity of MAGE-A10-specific CTLs in lung cancer cell lines and primary lung cancer cells.
Biotinylated:
no
Description:
Recombinant Human HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus, tetramer is assembled by biotinylated monomer and streptavidin.It contains Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and GLYDGMEHL peptide.
Endotoxin:
Less than 1EU per ug by the LAL method.
Exact Sequence:
Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and GLYDGMEHL peptide
Expression System:
HEK293
Form:
Lyophilized
Formulation:
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Gene/Protein ID:
A0A140T913(HLA-A*02:01)&P61769(B2M)&GLYDGMEHL
Molecular Weight:
The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reducing (N) condition based on Bis-Tris PAGE result.
Purity:
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Reconstitution:
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Tag:
C-His-Avi
Target:
HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Tetramer

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