KactusBio Inc.

Human HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Tetramer Protein (MHC-HM439T)

Product Code:
 
KAC-MHC-HM439T
Product Group:
 
MHC Tetramers
Supplier:
 
KactusBio Inc.
Host Type:
 
HEK 293 cells
Regulatory Status:
 
RUO
Target Species:
 
Human
Shipping:
 
Shipped at ambient temperature.
Storage:
 
-20 to -80°C for 12 months as supplied from date of receipt.-80°C for 3 months after reconstitution.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Human HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Tetramer?Protein on Bis-Tris PAGE under Non reducing (N) condition. The purity is greater than 95%
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The purity of Human HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Tetramer is greater than 90% as determined by SEC-HPLC.
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Human HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Tetramer?Protein on Bis-Tris PAGE under Non reducing (N) condition. The purity is greater than 95%
The purity of Human HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Tetramer is greater than 90% as determined by SEC-HPLC.

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CodeSizePrice
KAC-MHC-HM439T-100UG100UG£676.00
Quantity:
KAC-MHC-HM439T-500UG500UG£2,463.00
Quantity:
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This product comes from: United States.
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Further Information

Background:
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
Biotinylated:
no
Description:
Recombinant Human HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus, tetramer is assembled by biotinylated monomer and streptavidin.It contains Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and VVVGACGVGK peptide.
Endotoxin:
Less than 1EU per ug by the LAL method.
Exact Sequence:
Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and VVVGACGVGK peptide
Expression System:
HEK293
Form:
Lyophilized
Formulation:
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Gene/Protein ID:
AAV53343.1(HLA-A*11:01)&P61769(B2M)&VVVGACGVGK
Molecular Weight:
The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reducing (N) condition based on Bis-Tris PAGE result.
Purity:
> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Reconstitution:
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Tag:
C-His-Avi
Target:
HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Tetramer

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