KactusBio Inc.

Human HLA-A*01:01&B2M&DSG3 (YTDNWLAVY) Monomer Protein (MHC-HM428)

Product Code:
 
KAC-MHC-HM428
Product Group:
 
MHC Monomers
Supplier:
 
KactusBio Inc.
Regulatory Status:
 
RUO
Target Species:
 
Human
Shipping:
 
Shipped at ambient temperature.
Storage:
 
-20 to -80°C for 12 months as supplied from date of receipt.-80°C for 3 months after reconstitution.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Human HLA-A*01:01&B2M&DSG3 (YTDNWLAVY) Monomer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%
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The purity of Human HLA-A*01:01&B2M&DSG3 (YTDNWLAVY) Monomer is greater than 95% as determined by SEC-HPLC.
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Human HLA-A*01:01&B2M&DSG3 (YTDNWLAVY) Monomer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%
The purity of Human HLA-A*01:01&B2M&DSG3 (YTDNWLAVY) Monomer is greater than 95% as determined by SEC-HPLC.

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CodeSizePrice
KAC-MHC-HM428-100UG100UG£327.00
Quantity:
KAC-MHC-HM428-500UG500UG£974.00
Quantity:
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This product comes from: United States.
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Further Information

Background:
DSG3 is overexpressed in head neck cancer and is a potential molecular target for inhibition of oncogenesis. DSG3 is identified overexpressed in HNC, with the degree of overexpression associated with clinicopathologic features of the tumor. Inhibition of DSG3 significantly suppresses carcinogenic potential in cellular and in vivo animal studies. These findings suggest that DSG3 is a potential molecular target in the development of adjuvant therapy for HNC.
Biotinylated:
no
Description:
Recombinant Human HLA-A*01:01&B2M&DSG3 (YTDNWLAVY) Monomer Protein is expressed from HEK293 with His tag and Avi Tag at the C-Terminus.It contains Gly25-Thr305(HLA-A*01:01), Ile21-Met119(B2M) and YTDNWLAVY peptide..
Endotoxin:
Less than 1EU per ug by the LAL method.
Exact Sequence:
Gly25-Thr305(HLA-A*01:01), Ile21-Met119(B2M)and YTDNWLAVY peptide.
Expression System:
HEK293
Form:
Lyophilized
Formulation:
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Gene/Protein ID:
Q5SUL5(HLA-A*01:01)&P61769(B2M)&YTDNWLAVY
Molecular Weight:
The protein has a predicted MW of 50.50 kDa. Due to glycosylation, the protein migrates to 52-62 kDa based on Bis-Tris PAGE result.
Purity:
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Reconstitution:
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Tag:
C-His-Avi
Target:
HLA-A*01:01&B2M&DSG3 (YTDNWLAVY) Monomer

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