KactusBio Inc.

PE-Labeled Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer Protein (HLG-HM41CTP)

Product Code:
 
KAC-HLG-HM41CTP
Product Group:
 
MHC Tetramers
Supplier:
 
KactusBio Inc.
Host Type:
 
HEK 293 cells
Regulatory Status:
 
RUO
Target Species:
 
Human
Shipping:
 
Shipped with dry ice.
Storage:
 
Valid for 6 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Immobilized PE-Labeled Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-HLA-G Antibody, hFc Tag with the EC50 of 10.6ng/ml determined by ELISA.
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Immobilized PE-Labeled Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-HLA-G Antibody, hFc Tag with the EC50 of 10.6ng/ml determined by ELISA.

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This product comes from: United States.
Typical lead time: 14-21 working days.
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Further Information

Background:
HLA-G is a molecule that was first known to confer protection to the fetus from destruction by the immune system of its mother, thus critically contributing to fetal-maternal tolerance. The first functional finding constituted the basis for HLA-G research and can be summarized as such: HLA-G, membrane-bound or soluble, strongly binds its inhibitory receptors on immune cells (NK, T, B, monocytes/dendritic cells), inhibits the functions of these effectors, and so induces immune inhibition.
Biotinylated:
no
Description:
Recombinant PE-Labeled Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus. PE-Labeled Human HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer is assembled by biotinylated monomer and PE-labeled streptavidin.It contains Gly25-Thr305 (HLA-G), Ile21-Met119 (B2M) and RIIPRHLQL peptide.
Endotoxin:
Less than 1EU per ug by the LAL method.
Exact Sequence:
Gly25-Thr305(HLA-G), Ile21-Met119(B2M) and RIIPRHLQL peptide
Expression System:
HEK293
Form:
Liquid
Formulation:
Supplied as 0.22um filtered solution in PBS, 0.2% BSA (pH 7.4).
Gene/Protein ID:
P17693-1(HLA-G)&P61769(B2M)&RIIPRHLQL
Tag:
C-His-Avi
Target:
HLA-G&B2M&Peptide (RIIPRHLQL) Tetramer

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